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Enrolling by invitation NCT06782087

A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent

Phase I Interventional Tooth Discoloration

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: nano chitosan.
Who it may be relevant to
Registry conditions: Tooth Discoloration. Basic parameters: 18 years — 40 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent :A Controlled Clinical Trial

Overview

The growing demand for white smile between patients has increased over recent years, the development of techniques and improvement of materials permits searching for beautiful natural smile. The discoloration of teeth might be intrinsic, extrinsic, or combined. A variety of commercial bleaching agents is available. The most common substances used are carbamide peroxide or hydrogen peroxide or a mixture of sodium perborate and hydrogen peroxide.

Detailed description

The aim of the study is to assess the effectiveness of two different in-office bleaching materials carbamide peroxide alone and carbamide peroxide with Chitosan nanoparticles Using diode laser as an activator Regarding tooth whitening and color stability 1 Day , 1 weeks, 1 month after treatment using Vita easy shade.

Interventions

  • Drug nano chitosan
    nano chitosan

Primary outcome measures

  • Color change [Time frame: these assessments were performed for 1 day, 1 week, and 1 month after treatment with Vita easy shade.]
  • color change using digital vita easy shade guide [Time frame: 1 day , 1 week , 1 month]

Eligibility criteria

Inclusion criteria

  • discolored crown, non-vital or endodontically treated upper central and lateral incisors
  • previous endodontic treatment performed two or more years earlier.

Exclusion criteria

  • caries on upper central and lateral incisors, inadequate fillings, and progressive periodontal disease.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
N/A
Model
Sequential
Masking
Open label
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Misr University for science and technology — Giza

Identifiers

NCT: NCT06782087 · 2022/0037

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗