Frequency and Predictors of Recurrent SBP in Cirrhotic Patients in Al Rajhi University Hospital
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Spontaneous Bacterial Peritonitis. Basic parameters: up to 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Frequency and Predictors of Recurrent Spontaneous Bacterial Peritonitis in Cirrhotic Patients in Al Rajhi University Hospital
Overview
* Assess the frequency of recurrent SBP in ascitic cirrhotic patients. * Determine the predictive factors of recurrence after the first episode of SBP in ascitic cirrhotic patients
Detailed description
Spontaneous bacterial peritonitis (SBP) is a common complication in cirrhotic patients. The prevalence of SBP in hospitalized patients and the mortality rate were reported to be 10%-30% and 30%-50%, respectively.
SBP has been considered a life-threatening infection that requires a prompt diagnosis and treatment.
Primary outcome measures
- Frequency and Predictors of Recurrent Spontaneous Bacterial Peritonitis in Cirrhotic Patients in Al Rajhi University Hospital. [Time frame: One year]
Secondary outcome measures (1)
- Predictors of recurrent SBP [Time frame: One year]
Eligibility criteria
Inclusion criteria
- Any cirrhotic patient above the age of 18 years old of both sexes, having a first episode of SBP will be included in our study.
- The diagnosis of cirrhosis was based on clinical manifestation (ascites, splenomegaly, lower limb edema and/or esophageal varices by upper gastrointestinal endoscopy), laboratory findings and radiological (abdominal ultrasonography), or liver histology.
- The diagnosis of SBP was based on a neutrophil cell count of 250 cell or more per mm3 with or without culture positivity of ascitic fluid, in the absence of hemorrhagic ascites and secondary peritonitis.
Exclusion criteria
- Any patient with one or more of the following criteria will be excluded:
- Patients with bacterial ascites defined by a positive culture of ascitic fluid associated with a neutrophil cell count less than 250 cell per mm3 in the ascitic fluid.
- Patients presenting with empyema or bacterial peritonitis secondary to an intra-abdominal organ perforation or surgical operation
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-control
Study locations
Egypt · 2 centers
- Assiut Faculty of Medicine — Asyut
- Assiut University — Asyut
Publications
- Moalla M, Elleuch N, Dahmani W, Hammami A, Ameur WB, Slama AB, Brahem A, Ajmi S, Ksiaa M, Jaziri H, Jmaa A. Predictive factors of recurrence in spontaneous bacterial peritonitis in Tunisian patients with cirrhosis. Future Sci OA. 2023 Apr 17;9(5):FSO857. doi: 10.2144/fsoa-2023-0016. eCollection 2023 Jun. PMID 37180608
Identifiers
NCT: NCT06778616 · Recurrence of SBP