Exergaming Training Among Hypertensive Patients

Official title

Effects of Exergaming Training on Balance Among Hypertensive Patients

Overview

Since Hypertension affects all body systems and importantly postural balance control. So, the evidence indicates a strong link and connection between balance and hypertension through somatosensory, visual, vestibular, musculoskeletal, and CNS integration of inputs from both peripheral and motor systems. Therefore, to fill this gap of how much balance and each of its aspects/components are affected, this study will be done for a detailed examination of this genuine integration and clinical interaction among hypertensive with game-based techniques on all three balance components (concerning Intensity, frequency, duration and dosage of VRET). Secondly, on the other hand (CR) programs, have shown very low compliance with recommended Physical Activity, which is why; by utilising this alternative, Virtual reality exergaming can be used as a quick, appropriate and equivalent alternative to traditional exercise programs. Also, in future, it could be suggested with promising effects in the provision of engaging, goal-oriented training for patients with hypertensive besides a sound, economical and clinically beneficial alternative to traditional Cardiac Rehabilitation. Finally, by exploring detailed clinical integration of Postural Balance with Hypertension using Virtual Reality the study will be able to highlight hypertension as a potent risk factor for future impaired balance and risks of falls. Thereby, hypertension's early identification (considering all biological, psychological, and social factors) and prevention may avert hypertensive to future debilitating complications and outcomes as a result of it.

Interventions

• Other Exercise
  The participants would be playing exergames using XBOX-360 Kinect. Multiple games would be selected for the participants to play. The player would be upgraded to next levels of games after completing the initial levels.
• Other Exercise
  The subjects would be doing treadmill training within moderate intensity target heart rate.
• Other No intervention
  The subjects would not be given any intervention and would be used as controls.

Primary outcome measures

• Gait and Balance App [Time frame: Baseline before provision of interventions]
• Gait and Balance App [Time frame: After 4 weeks of interventions]
• Gait and Balance App [Time frame: After 8 weeks of interventions]
• Brain-derived neurotrophic factor (BDNF) biomarker: [Time frame: Baseline before provision of interventions]
• Brain Derived Neurotrophic Factor Biomarker [Time frame: After 8 weeks of interventions]
• Exercise Enjoyment Questionnaire (EEQ) [Time frame: After 8 weeks of interventions]
• The Montreal Cognitive Assessment (MoCA) [Time frame: Baseline before provision of interventions]
• Montreal Cognitive Assessment (MoCA) [Time frame: After 4 weeks of interventions]
• Montreal Cognitive Assessment (MoCA) [Time frame: After 8 weeks of interventions]
• 3 Min Walk Test [Time frame: Baseline before provision of interventions]

Eligibility criteria

Inclusion criteria

• Diagnosis of Community dwelling controlled Hypertensive (particularly Stage 1, 130 to 139 (systolic) or 80 to 89 (diastolic) or Stage 2 hypertension from 140 or higher (systolic) or 90 (diastolic) if present with any (controlled diabetes or overweight patients) with a medical referral form for medical specialist with physiotherapeutic treatment provided by the local public or private healthcare system
• Any race or gender with age 20 or older
• No history of any orthopedic, neurological, Pulmonary or psychological disorders, Cognitive impairments etc.
• Had not performed physical activity in the previous three months.

Exclusion criteria

• Grade III or grade IV heart failure according to the New York Heart Association (NYHA) Functional Classification.
• Recent acute myocardial infarction; unstable angina; acute pericarditis. pulmonary hypertension; uncontrolled diabetes mellitus; Hypertensive crises or uncontrolled Hypertension or Pregnancy
• Patients who had three consecutive absences during the intervention
• Unable to answer or understand the gaming or exercise protocols and quality of life questionnaires and fulfil the exercise protocols, due to any severe cognitive deficit
• Pain with ambulation or dizziness when standing or walking.
• Contraindications to treadmill walking or VR gaming

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation

Randomized

Model

Parallel assignment

Masking

Single blind

Primary purpose

Treatment

Study locations

Pakistan · 1 center

• Foundation University — Islamabad

Identifiers

NCT: NCT06777927 · RIPHAH/RCRS/REC/Letter-01198

Primary sources (government registries)

• ClinicalTrials.gov (US NIH)

View this study on ClinicalTrials.gov ↗