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Enrolling by invitation NCT06774157

Evaluation of the Efficacy of the ALLYANE Procedure in the Treatment of Central Motor Inhibition

No phase Interventional Arthrogenic Muscle Inhibition Arthrogenic Muscle Inhibitions

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: A session combining motor imagery and listening to low frequency sounds, Standard management - Control group, Standard management - Control group, Standard management - Control group.
Who it may be relevant to
Registry conditions: Arthrogenic Muscle Inhibition, Arthrogenic Muscle Inhibitions. Basic parameters: 18 years — 35 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Evaluation of the Efficacy of the ALLYANE Procedure in the Treatment of Central Motor Inhibition Immediately After Knee Sprain as an Adjunct to Conventional Treatment.

Overview

The goal of this clinical study is to determine the effectiveness of restoring muscle strength in the management of motor inhibition when complemented by the ALLYANE process (neuro-motor reprogramming) compared to a standard management approach. The main questions it aims to answer are: * Does the ALLYANE process lead to greater muscle strength gains compared to standard care? * Is there a functional benefit when standard management is complemented by the ALLYANE process? The investigators will compare the group receiving standard care complemented by ALLYANE to a group receiving only standard care to evaluate if the ALLYANE process provides additional effects. Participants will: * Undergo assessments of muscle strength. * Receive either standard management or standard management with ALLYANE. * Complete functional evaluations before and after treatment.

Detailed description

This study aims to evaluate the effectiveness of motor inhibition management using two different approaches: standard management alone and standard management supplemented by the ALLYANE neuro-motor reprogramming process. To ensure robust and reliable results, the study proposes enrolling a total of 120 patients, divided into two groups of 60 patients each.

Interventions

  • Other A session combining motor imagery and listening to low frequency sounds
    Prospective study of the efficacy of the Allyane procedure after knee sprain
  • Other Standard management - Control group
    Active extension (e.g. by lateral raising of the quadriceps, strengthening of the quadriceps) quadriceps)
  • Other Standard management - Control group
    Flexor inhibition (e.g. massage, hamstring stretching)
  • Other Standard management - Control group
    Active flexion (e.g. strengthening the flexors)

Primary outcome measures

  • Muscle activity [Time frame: Before and 3 weeks after conventional therapy]
Secondary outcome measures (1)
  • Strength [Time frame: Before and 3 weeks after conventional therapy]

Eligibility criteria

Inclusion criteria

  • Men and women aged 18 to 35 years
  • No neurological history
  • Have had a primary knee sprain
  • Present with VMO lateralisation with or without the presence of flessum
  • Quadricipital weakness between the healthy and injured limb of 50% or more as measured by a portable dynamometer
  • Member of a social security scheme

Exclusion criteria

  • Recurrent sprain
  • Bilateral sprain
  • Persons under guardianship, trusteeship or any other measure depriving them of their rights or liberty, and adults protected by law.
  • Persons who do not understand French
  • Knee trauma other than sprain
  • Exclusion criteria for the Allyane procedure (COPHOSIS, cognitive difficulties, purely mechanical limitation)
  • Algodystrophy

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

France · 1 center
  • Centre Expert du Mouvement — Lyon

Publications

  • Dos Anjos T, Gabriel F, Vieira TD, Hopper GP, Sonnery-Cottet B. Neuromotor Treatment of Arthrogenic Muscle Inhibition After Knee Injury or Surgery. Sports Health. 2024 May-Jun;16(3):383-389. doi: 10.1177/19417381231169285. Epub 2023 Apr 27. PMID 37102673

Identifiers

NCT: NCT06774157 · AMI_LCA

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗