Menu
Recruiting NCT06773611

Electronic Register on Advanced Heart Failure and Transplantation di Cuore

Observational Heart Failure Heart Transplantation

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Heart Failure, Heart Transplantation. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Electronic Register on Advanced Heart Failure and Transplantation

Overview

The goal of this observational study is to create an electronic registry of patients diagnosed with Advanced Heart Failure or Heart Transplant, starting from 01/01/1985 and to assess the incidence of Advanced Heart Failure and Heart Transplant, and characterize patients affected by the first or undergoing the second procedure, starting from 01/01/1985. The primary outcomes are: * Hospitalization for cardiovascular cause * Death

Detailed description

Heart failure is a pathological condition characterized by high morbidity and mortality, and it leads to a significant worsening of the quality of life for patients. The treatment of heart failure involves various options; the goal is to slow down the progression of the disease, reduce hospitalizations, increase survival, and reduce symptoms in order to improve the quality of life. Treatments range from pharmacological therapy to lifestyle changes, from device implantation to heart transplant surgery. Early diagnosis and treatment often help reduce symptoms, and many patients with heart failure can return to an active life. Patients with heart failure must undergo regular check-ups to assess their general physical condition and the status of the disease. It is therefore essential to evaluate and systematize the different therapies.

This study is both retrospective and prospective

Primary outcome measures

  • Hospitalization for cardiovascular cause [Time frame: 5 years]
  • Death [Time frame: 5 years]
Secondary outcome measures (4)
  • Hospitalization for non-cardiovascular cause [Time frame: 5 years]
  • Implantation of medical device (including mechanical support) [Time frame: 5 years]
  • Need for intravenous diuretic therapy [Time frame: 5 years]
  • Need for hemodialysis event [Time frame: 5 years]

Eligibility criteria

Inclusion criteria

  • Age ≥ 18 years
  • Ability to provide informed consent
  • Diagnosis of Advanced Heart Failure or Heart Transplant

Exclusion criteria

  • none

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Italy · 1 center
  • IRCCS Azienda Ospedaliero-Universitaria di Bologna — Bologna

Identifiers

NCT: NCT06773611 · Rescat

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗