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Not yet recruiting NCT06771375

Eye Movement Desensitization and Reprocessing (EMDR) to Treat Chronic Pruritus

No phase Interventional Chronic Pruritus

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Eye Movement Desensitization and Reprocessing.
Who it may be relevant to
Registry conditions: Chronic Pruritus. Basic parameters: 18 years — 75 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Switzerland
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Eye Movement Desensitization and Reprocessing (EMDR) to Treat Chronic Pruritus in a Multidisciplinary Tertiary Care Setting- a Feasibility Study

Overview

Pruritus is a common symptom of numerous dermatological and non-dermatological conditions. Current treatments for chronic pruritus (CP) are often not fully effective and may have burdensome side effects. Recently, the trauma exposure technique Eye Movement Desensitization and Reprocessing (EMDR) that is recommended as first line treatment for posttraumatic stress disorder has been reported to be also effective in the treatment of CP in anecdotal clinical case observations. However, to the best of the investigator's knowledge, the efficacy of EMDR in CP has not yet been systematically explored. This study aims at addressing this unmet need in a prospective pilot study comparing EMDR versus treatment as usual (TAU).

Interventions

  • Behavioral Eye Movement Desensitization and Reprocessing
    EMDR is a psychotherapeutic approach originally designed for individuals suffering from trauma and post-traumatic stress disorder (PTSD). It facilitates the processing of memories through a structured eight-phase treatment, involving the patient's focused attention on traumatic images, thoughts, and sensations while simultaneously engaging in bilateral stimulation, typically through guided eye movements. This process aims to reduce the emotional distress associated with aversive memories, promot

Primary outcome measures

  • Adherence (%) [Time frame: up to 8 month]

Eligibility criteria

Inclusion criteria

  • Provided written informed consent
  • Age 18 to 75 years
  • Skindex-29 (questionnaire) symptoms subscale ≥42
  • Confirmed diagnosis CP
  • Itch intensity of min. ≥ 4 on the 0-10 numerical rating scale within the last 7 days
  • Stable course of treatment in the two weeks prior to the study

Exclusion criteria

  • Inability to follow the procedures of the study, e.g. due to language problems, severe psychiatric disorders such as delusional disorder, suicidality or dementia.
  • Patients on phototherapy
  • Acute attacks of an autoimmune disease such as Crohn's disease
  • Serious cardiac disease

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Non-randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

Switzerland · 1 center
  • University Hospital Basel — Basel

Identifiers

NCT: NCT06771375 · 2024-02597, th24schaefert

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗