Recruiting NCT06767579
Comparison of the Incidence of Delirium Caused by Different Anesthetic Agents in Patients Undergoing Liver Transplantation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Hepatocellular Carcinoma, Liver Cirrhosis. Basic parameters: from 19 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- South Korea
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This study is a prospective observational study that analyzes the incidence of postoperative delirium in patients undergoing liver transplantation, based on the use of the inhalational anesthetic sevoflurane and the intravenous anesthetic propofol.
Primary outcome measures
- incidence of postoperative delirium [Time frame: from postoperative day 0 to postoperative day 7]
Secondary outcome measures (4)
- comprehensive geriatric assessment(CGA) [Time frame: Participants will be followed for the duration of their hospital stay and until their visit within one month after discharge, with an expected average of 4 weeks]
- duration of delirium [Time frame: Participants will be followed for the duration of their hospital stay and until their visit within one month after discharge, with an expected average of 4 weeks]
- total score of QOR-40 [Time frame: Participants will be followed for the duration of their hospital stay and until their visit within one month after discharge, with an expected average of 4 weeks]
- type of delirium [Time frame: Participants will be followed for the duration of their hospital stay and until their visit within one month after discharge, with an expected average of 4 weeks]
Eligibility criteria
Inclusion criteria
- Adults aged 19 years and older
- Patients undergoing liver transplantation who are scheduled to receive anesthesia with the inhaled anesthetic sevoflurane or the intravenous anesthetic propofol.
Exclusion criteria
- Individuals with hearing loss, cognitive impairment or obvious dementia, hepatic encephalopathy, or difficulty in communication.
- Diagnosed with neurological disorders (e.g., brain hemorrhage, stroke, dementia, Parkinson's disease, cognitive impairment, etc.).
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-control
Study locations
South Korea · 1 center
- Department of Anesthesiology and Pain Medicine Yonsei University College of Medicine — Seoul
Identifiers
NCT: NCT06767579 · 4-2024-1084