Evaluation of Upper Extremity Functions in Obesity Hypoventilation Syndrome Patients
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In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Assessment.
- Who it may be relevant to
- Registry conditions: Obesity Hypoventilation Syndrome (OHS). Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Evaluation of Upper Extremity Functions in Patients with Obesity Hypoventilation Syndrome
Overview
Obesity Hypoventilation Syndrome (OHS) is a disease characterized by daytime hypercapnia and sleep-related respiratory disturbances in individuals with a body mass index (BMI) greater than 30 kg/m², without any other condition that could lead to hypoventilation. Although various mechanisms play a role in the pathogenesis of OHS, the most significant one is the altered respiratory system mechanics due to obesity. Obesity also leads to a decrease in peripheral muscle strength and exercise capacity. It has been reported that in obese individuals, not only general body movements and lower extremities but also upper extremity movements are negatively affected. Specifically, it has been observed that during activities against gravity, movement speed is low while the duration of movement is high. In OHS patients, daily living activities, physical activity, and exercise capacity are also negatively impacted. Supported or unsupported arm movements are of great importance in performing daily living activities. The muscles activated during both simple arm lifting and combined movements also function as accessory respiratory muscles. In individuals with cardiopulmonary diseases, an increase in the respiratory workload, especially during unsupported arm movements, has been observed. It is thought that in OHS patients, both the effects of obesity and the respiratory system may limit upper extremity functions. However, no studies have evaluated upper extremity functions in these individuals. Therefore, the aim of investigators study is to evaluate upper extremity functions in OHS patients.
Detailed description
The study will include patients diagnosed with Obesity Hypoventilation Syndrome, who are followed at the Department of Chest Diseases, Istanbul University Faculty of Medicine. The study will be conducted in accordance with the Helsinki Declaration, and an informed consent form will be obtained from the participants who are willing to take part in the study. Before the study begins, the participants will be informed about the purpose of the study and provided with all relevant details. Participants who agree to participate will be invited to the Chest Diseases Department of Istanbul University Faculty of Medicine. Demographic information of the participants will be recorded, followed by the evaluation of body composition, upper extremity functional exercise capacity, grip strength, and activities of daily living. The main aim of the study is to comprehensively investigate the upper extremity functions in patients with OHS.
Interventions
- Other Assessment
31 volunteer participants who were followed up at the Department of Chest Diseases, Istanbul University, Istanbul Faculty of Medicine and met the inclusion criteria were included in the study. Participants' body composition, upper extremity functional exercise capacity, grip strength, and activities of daily living were evaluated.
Primary outcome measures
- 6-Minute Pegboard and Ring Test - Upper Extremity Functional Exercise Capacity [Time frame: 1 day]
- Milliken Activities of Daily Living Scale [Time frame: 1 day]
- Grip Strength [Time frame: 1 day]
- The Glittre Activities of Daily Living Test [Time frame: 1 day]
Secondary outcome measures (9)
- Body Mass Index [Time frame: 1 day]
- Anthropometric Measurements - Waist Circumference [Time frame: 1 day]
- Anthropometric Measurements - Hip Circumference [Time frame: 1 day]
- Anthropometric Measurements - Neck Circumference [Time frame: 1 day]
- Anthropometric Measurements - Arm Circumference [Time frame: 1 day]
- The Waist-Hip Ratio [Time frame: 1 day]
- Body Fluid Percentage [Time frame: 1 day]
- Body Fat Percentage [Time frame: 1 day]
- Muscle Mass [Time frame: 1 day]
Eligibility criteria
Inclusion criteria
- Individuals between the ages of 18-65
- Individuals diagnosed with OHS by a Chest Disease Specialist
Exclusion criteria
- Individuals with neurological or orthopedic problems that prevent them from performing the tests or understanding the scales applied within the scope of the study
- Additional pulmonary disease
- Uncontrolled cardiovascular disease
- Presence of uncontrolled diabetes
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
Turkey (Türkiye) · 1 center
- Istanbul University-Cerrahpasa — Istanbul
Identifiers
NCT: NCT06766110 · IUC-FTR-NYildiz-01