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Recruiting NCT06765486

Exercise-Induced Hypoalgesia Differences Between Upper and Lower Limbs Resistance Training Interventions

No phase Interventional Local Hypoalgesia Distal Hypoalgesia Resistance Training Pressure Pain Thresholds

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Lower limb resistance training, Upper limb resistance training.
Who it may be relevant to
Registry conditions: Local Hypoalgesia, Distal Hypoalgesia, Resistance Training, Pressure Pain Thresholds. Basic parameters: 18 years — 64 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Spain
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Exercise-Induced Hypoalgesia Differences at Proximal and Distal Regions After Applying a Lower Limb Resistance Training or an Upper Limb Resistance Training Protocol: A Randomized Controlled Trial in Healthy Participants

Overview

This randomized controlled trial with healthy subjects aims to compare exercise-induced hypoalgesia among three groups: one utilizing a lower limb resistance training intervention, another using an upper limb resistance training, and a control group. The exercise protocol involves 3 sets of 5 repetitions of resistance exercises (brachial biceps curl and leg extensions). Exercise-induced hypoalgesia will be assessed by measuring pressure pain thresholds in the thigh and elbow, comparing exercise interventions with the control group. Additionally, a secondary objective is to compare the lower limb and upper limb resistance training groups in terms of their effects on pressure pain thresholds in the thigh and elbow. Thus, the study anticipates observing differences in local and distal hypoalgesia based on the trained region.

Interventions

  • Other Lower limb resistance training
    Exercise intervention with leg extensions on the dominant quadriceps, doing 3 sets of 5 repetitions with the 5RM after a 5-minute warm-up with a cycle ergometer at 1 watt per kg and 60-80 revolutions per minute and 1 set of 5 repetitions with the 10RM. Previously, 72 hours before, the 5RM would have been calculated progressively approaching in sets of 5 repetitions, starting with the lower weight and stopping the test when obtaining an unsuccessful trial (the participant could not manage to lift
  • Other Upper limb resistance training
    Exercise intervention with brachial biceps curl on the dominant brachial biceps, doing 3 sets of 5 repetitions with the 5RM after a 5-minute warm-up with a cycle ergometer at 1 watt per kg and 60-80 revolutions per minute and 1 set of 5 repetitions with the 10RM. Previously, 72 hours before, the 5RM would have been calculated progressively approaching in sets of 5 repetitions, starting with the lower weight and stopping the test when obtaining an unsuccessful trial (the participant could not man

Primary outcome measures

  • Pain pressure threshold (PPT) on dominant quadriceps and dominant brachial biceps [Time frame: before, immediately after intervention, and 30 minutes after intervention.]
Secondary outcome measures (4)
  • International Physical Activity Questionnaire (IPAQ) [Time frame: before intervention (up 5 minutes)]
  • Physical Activity Readiness Questionnaire (PAR-Q) [Time frame: before intervention (up 5 minutes)]
  • Fatigue Assessment Scale (FAS) [Time frame: before intervention (up 5 minutes)]
  • Rate of perceived exertion (RPE) [Time frame: immediately after intervention (up 10 seconds)]

Eligibility criteria

Inclusion criteria

  • Asymptomatic subjects aged between 18 and 64 years.

Exclusion criteria

  • Cardiovascular, respiratory, metabolic, neurological, or osteomuscular signs or pathologies.
  • History of epilepsy.
  • Pregnant.
  • Participants who present any type of pain on the day of the measurements or who have frequently suffered pain during the previous 12 weeks.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Spain · 1 center
  • CSEU LaSalle — Madrid

Identifiers

NCT: NCT06765486 · CSEULS-PI-013

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗