Cryopreserved Hair Follicles for Disease and Cell Replacement
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Diabetes Mellitus, Sport Injury, Injury Traumatic. Basic parameters: 18 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Canada
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Characterization of Cryopreserved Plucked Hair Follicles and Generation of Functional Cell Lines for Disease Modeling and Cell Replacement Therapies
Overview
To explore the application of cells expanded from plucked hair follicles after collection, transport, and cryopreservation, in disease modeling and cell-based therapies.
Detailed description
Hair Follicles collected and transported in Acorn's proprietary transport media can serve has therapeutic starting materials for future cell-based therapeutics. This study is to characterize primary cell outgrowth, functional stem cell generation and induced pluripotent stem cell line(s) from primary outgrowth(s) as well as evaluate and characterize differentiation of stem cell lines into functional cell types required for various disease states and cell-based application(s).
Primary outcome measures
- Characterize primary cellular outgrowth(s) [Time frame: 30 days]
- Evaluate functional stem cell generation and induced pluripotent stem cell line(s) from primary outgrowth(s) [Time frame: 21 days]
- Evaluate and characterize differentiation of stem cell lines into functional cell types required for various disease states and cell-based application(s) [Time frame: 30 days]
Eligibility criteria
Inclusion criteria
- Gender: Male or Female.
- Age: ≥18 and ≤80 years.
- Language proficiency: Able to read and understand English.
- Informed consent: Willing to provide written, informed consent to participate in all study activities.
Exclusion criteria
- Scalp/Hair Disorders: Subjects diagnosed with active scalp infections or inflammatory skin conditions.
- Systemic Conditions: Subjects with chronic illnesses, such as autoimmune diseases or diabetes, that may impact scalp health or wound healing.
- Medications: Subjects on immunosuppressants, steroids, or other medications associated with hair loss.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
Canada · 1 center
- Acorn Biolabs — Toronto
Identifiers
NCT: NCT06764719 · 24-003 · Company Sponsored