Cardiac Magnetic Resonance Predictors of Outcome of Rhythm Control in Patients with Atrial Fibrillation/Flutter
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Rhythm Monitoring. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
evaluate the impact of various features in CMR on the mid-term/long-term success rate of rhythm control for paroxysmal atrial fibrillation/flutter .
Detailed description
* Atrial fibrillation/flutter are widely prevalent. * Reported antiarrhythmic drug efficacy to restore \& maintain sinus rhythm is 52% which is far from optimal. * On the other hand, 5-year arrhythmia-free survival after catheter ablation was previously reported to be 63%. * Therefore, there is a need for better characterization of the underlying atrial substrate, to improve treatment outcomes in terms of efficacy and safety
Primary outcome measures
- Recurence in patient with AF or flutter after pharmacological or interventional rythm control [Time frame: Baseline]
Secondary outcome measures (1)
- parameters for safe ablation [Time frame: Baseline]
Eligibility criteria
Inclusion criteria
- Age>18 years.
- Patients undergoing successful cardioversion (pharmacologic or electric) for atrial fibrillation/flutter, OR symptomatic patients with paroxysmal atrial fibrillation/flutter scheduled for trans-catheter ablation.
- Index cardioversion OR Index ablation procedure.
Exclusion criteria
- LA thrombus on TEE or CMR.
- Contraindications to CMR.
- Contraindications to Gd-based contrast.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Egypt · 1 center
- Assiut Univeristy Heart Hospital — Asyut
Publications
- 1. Calkins H et al. Circ Arrhythm Electrophysiol. 2009
Identifiers
NCT: NCT06758895 · CMR in rythm control