Recruiting NCT06755866
DCE-MRI Based on 4D Free Breathing for Predicting Preoperative Neoadjuvant Chemoradiotherapy for Esophageal Cancer
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: The application value of MRI 4D Free Breathing DCE-MRI in the treatment of esophageal cancer.
- Who it may be relevant to
- Registry conditions: Esophageal Cancer. Basic parameters: 18 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
To prospectively collect medical images and clinical data related to esophageal cancer using 4D Free Breathing DCE-MRI technology, to evaluate the image quality in the diagnosis of esophageal cancer, and to predict the efficacy of preoperative neoadjuvant chemoradiotherapy for esophageal cancer.
Interventions
- Diagnostic test The application value of MRI 4D Free Breathing DCE-MRI in the treatment of esophageal cancer
Chest MRI scan outside of standard treatment options
Primary outcome measures
- Tumor response assessment [Time frame: Surgery was performed within one month after neoadjuvant therapy, and the pathological pCR of the pathological results obtained from the surgery was used as the gold standard in this study to evaluate tumor treatment response]
Eligibility criteria
Inclusion criteria
- Be 18 years of age and older;
- First diagnosis of esophageal squamous cell carcinoma confirmed by histopathological biopsy;
- The clinical stage is cT1b\~cT2N+; or the clinical stage is cT3\~cT4 any N, (thoracic esophageal cancer, esophagogastric junction cancer);
- There are no contraindications to MRI examination
Exclusion criteria
- Have other primary tumors;
- The image quality does not meet the diagnostic criteria;
- Those who do not cooperate with the inspection;
- Patients who have received prior chemoradiotherapy
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
China · 1 center
- Yunnan Cancer Hospital — Kunming
Identifiers
NCT: NCT06755866 · KYLX2024-273