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Not yet recruiting NCT06755502

Garlic Oil As Root Filling Material in Primary Molars

No phase Interventional Irreversible Pulpitis (toothache)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Garlic oil, Calcium Hydroxide, Iodoform, paste.
Who it may be relevant to
Registry conditions: Irreversible Pulpitis (toothache). Basic parameters: 4 years — 8 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Evaluation of Allium Sativum As Root Filling Material for Primary Molars Indicated for Non Vital Pulp Therapy: Randomized Clinical Trials

Overview

The goal of this study is to test garlic oil mixed with zinc oxide as a potential root canal filling material of primary molars in children aged from four to eight years. the study hypothesized that garlic oil mixed with zinc oxide would be the same as the gold standard filling material (metapex). The group receiving the garlic oil with zinc oxide as root canal filling material will be compared with other similar group receiving metapex as root canal filling material in terms of clinical and radio-graphic success, and working time.

Detailed description

This study is a randomized clinical trial (RCT), that aims compare the clinical and radio-graphic success of garlic oil mixed with zinc oxide, used as root canal filling material in primary molars in children aged from four to eight years, with the conventional root filling material, which is metapex.

Interventions

  • Combination product Garlic oil
    garlic oil mixed with zinc oxid powder, as root canal filling material
  • Drug Calcium Hydroxide, Iodoform, paste
    Metapex as root canal filling materials

Primary outcome measures

  • The clinical success rate [Time frame: 3, 6,9,and 12 months]
  • Radio-graphic success [Time frame: 6, and 12 month.]

Eligibility criteria

Inclusion criteria

  • Primary second molars which are diagnosed with irreversible pulpitis, or pulp necrosis.
  • Presence of sinus tract.
  • Periapical bone swelling.
  • Continuous bleeding after amputation of the coronal pulp tissue.
  • No pulp tissue remains when the pulp chamber is accessed.
  • Pus discharges from the canal.
  • Radiographically, only primary molars with at least two-thirds of the root length.
  • Presence of inter-radicular or periapical radiolucency.

Exclusion criteria

1\. A tooth with internal root resorption will not be included. 2. Excessive tooth mobility beyond healing. 3. Carious perforation in the pulpal flour. 4. A tooth with a pathological lesion extending to the successor's tooth germ. 5. Non-restorable primary molars.

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Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Triple blind
Primary purpose
Treatment

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT06755502 · 555

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗