Not yet recruiting NCT06751095

Effects Of Maitland's Mobilization At Mid Versus End Range In Knee Osteoarthritis Patients

No phase Interventional Knee Osteoarthritis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied: The protocol lists: Maitland's Mobilization in End range, Maitland's mobilization in Mid range.
Who it may be relevant to: Registry conditions: Knee Osteoarthritis. Basic parameters: 40 years — 60 years · All.
What needs checking: Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place: Center list to be confirmed — check the primary protocol.
Next step: Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Effects Of Maitland's Mobilization At Mid Versus End Range On Pain, Range Of Motion And Functional Disability In Patients With Knee Osteoarthritis.

Overview

Knee Osteoarthritis (OA) is the most common form of arthritis affecting mostly elderly people contributing to major cause of disability worldwide.In knee osteoarthritis Maitland's manual therapy technique could be the most effective technique among all in decreasing pain sensitivity and increasing range of motion in knee OA.The aim of this study to compare effects of Maitland's mobilization at mid range versus end range on pain. range of motion and functional disability in patients with knee OA, providing useful insights for healthcare professionals to optimize treatment strategies and enhance outcomes in this context.

Detailed description

This Randomized Clinical Trial will be conducted at DHQ Gujrat through consecutive sampling technique on 44 patients which will be allocated using simple random sampling through sealed opaque enveloped into (Group A and Group B).Maitland's mobilization at end range(Group A) incorporates the end range Maitland's mobilization,strengthening exercises, knee isometrics, transcutaneous electrical stimulation(TENS) and heating pad .

Maitland's mobilization in Mid range (Group B) will be treated with Mid range Maitland's mobilization, TENS,strengthening exercises,knee isometrics and heating pad.Outcomes, encompassing pain levels, range of motion(ROM), and functional disability will be evaluated through Visual analogue scale (VAS),Goniometer and WOMAC scale.The treatment plan spans 4 weeks, comprising 3 sessions per week. Data will be analyzed during SPSS software version 25. After assessing normality of data by Shapiro-wilk test, it will be decided either parametric or non-parametric test will be used within a group or between two groups. Data will be collected at baseline and after 4 weeks of follow up.

Interventions

Other Maitland's Mobilization in End range
End-range mobilization will be performed individually in flexion and extension end range of the tibiofemoral joint .(0-135 degree)
Other Maitland's mobilization in Mid range
Mid range Maitland's mobilization will be performed in (approx. 50-70° knee flexion) of the tibiofemoral joint

Primary outcome measures

Numeric Pain Rating Scale [Time frame: 4 Weeks]

Secondary outcome measures (2)

WOMAC Osteoarthritis INDEX [Time frame: 4 weeks]
Universal Goniometer [Time frame: 4 weeks]

Eligibility criteria

Inclusion criteria

Participants with age between 40 to 60 years.
Participants of both genders will be included.
Patient with unilateral/bilateral symptomatic tibiofemoral knee OA.
Patient suffering from stiffness less than 30 minutes
Patients with radiologically diagnosed case of grade 2 knee OA according to the Kellgren and Lawrence scale
Patients with reported peak knee pain of >3 on visual analogue scale (VAS)

Exclusion criteria

Participants with acute inflammation of knee
Participants with severe degenerative lumbar spine disease e.g spondylolisthesis
Participants with systemic inflammatory arthritic or neurological conditions
Participants with intraarticular injection in the prior 3 months
Participants with unstable heart condition
Participants with received physical therapy of knee in last 3 months

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation: Randomized
Model: Parallel assignment
Masking: Double blind
Primary purpose: Treatment

Study locations

Center list to be confirmed — check the primary protocol.

Publications

Suzuki Y, Iijima H, Tashiro Y, Kajiwara Y, Zeidan H, Shimoura K, Nishida Y, Bito T, Nakai K, Tatsumi M, Yoshimi S, Tsuboyama T, Aoyama T. Home exercise therapy to improve muscle strength and joint flexibility effectively treats pre-radiographic knee OA in community-dwelling elderly: a randomized controlled trial. Clin Rheumatol. 2019 Jan;38(1):133-141. doi: 10.1007/s10067-018-4263-3. Epub 2018 Aug PMID 30167975
Steultjens MP, Dekker J, van Baar ME, Oostendorp RA, Bijlsma JW. Range of joint motion and disability in patients with osteoarthritis of the knee or hip. Rheumatology (Oxford). 2000 Sep;39(9):955-61. doi: 10.1093/rheumatology/39.9.955. PMID 10986299
Pozsgai M, Udvaracz K, Peter IA, Than P, Nusser N. Effect of single end-range and not end-range Maitland mobilization on pressure pain threshold and functional measures in knee osteoarthritis: randomised, controlled clinical trial. Eur J Phys Rehabil Med. 2022 Oct;58(5):774-783. doi: 10.23736/S1973-9087.22.07506-2. Epub 2022 Sep 12. PMID 36094367

Identifiers

NCT: NCT06751095 · REC/RCR&AHS/24/0114

Primary sources (government registries)

ClinicalTrials.gov (US NIH)

View this study on ClinicalTrials.gov ↗