Recruiting NCT06741137
A Pilot Study of the Effect of the Combination of Inhaled Nitric Oxide and Prone Position Under EIT Monitoring on Efficacy in Patients with ARDS
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: inhaled nitric oxide combined with prone position ventilation.
- Who it may be relevant to
- Registry conditions: ARDS. Basic parameters: 18 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Investigating the Impact of Combined Inhaled Nitric Oxide and Prone Positioning on the Efficacy in ARDS Patients
Interventions
- Procedure inhaled nitric oxide combined with prone position ventilation
inhaled nitric oxide combined with prone position ventilation
Primary outcome measures
- Intratidal gas distribution [Time frame: 12 hours]
Eligibility criteria
Inclusion criteria
- Age 18-80 years;
- Patients with moderate to severe ARDS on mechanical ventilation
Exclusion criteria
- Patients with severe asthma or acute exacerbation of chronic obstructive pulmonary disease (COPD), lung tumors, post-lung resection, and post-lung transplantation.
- Patients with hemodynamic instability requiring vasopressor support: dopamine or dobutamine >15 µg/kg/min, norepinephrine >0.3 µg/kg/min.
- Cardiogenic pulmonary edema.
- Patients with severe facial deformities, facial trauma, or severe thoracoabdominal trauma that precludes prone positioning ventilation.
- Mid to late pregnancy.
- Patients with a history of malignancy or other irreversible diseases/conditions, including those in the terminal stage.
- Patients expected to be discharged soon or requiring invasive mechanical ventilation for less than 24 hours.
- Patients currently participating in other studies.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
China · 1 center
- Northern Jiangsu People's Hospital — Yangzhou
Identifiers
NCT: NCT06741137 · 2024ky074