Association Between Blood Pressure and Risk of PSCI
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Stroke, Cognitive Decline, Blood Pressure. Basic parameters: 18 years — 90 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Association Between Blood Pressure and the Risk of Post-stroke Cognitive Impairment: a Retrospective Cohort Study
Overview
This retrospective cohort study was designed to explore the relationship between blood pressure and cognitive impairment after stroke
Detailed description
Patients who have been followed up for more than 3 months after stroke will be included in the study. Basic data of patients and factors that may be related to cognitive impairment will be collected, and the relationship between blood pressure and cognitive impairment after stroke will be explored by univariate regression analysis and multivariate regression analysis. Univariate logistic regression model and multivariate logistic regression model were used to explore the relationship between blood pressure level and the risk of cognitive impairment after stroke, and the effect of blood pressure level and cognitive impairment sub-line in different patients was evaluated by subgroup analysis.
Primary outcome measures
- Mental State Examination Scale (MMSE) [Time frame: Mini-Mental State Examination (MMSE) assessment will be completeed at 3 monthes after stroke]
Eligibility criteria
Inclusion criteria
- Patient diagnosed with stroke by CT or MRI,
- Patients completed the MMSE scale at least once during hospitalization
- The follow-up time was more than three months after the stroke occurred;
Exclusion criteria
- Patients with incomplete data, follow-up time less than three months after the stroke occurred less than 3 months,
- Patients with pre-existing cognitive impairment before stroke according to their medical records,
- patients failed to complete MMSE assessment because of aphasia or any other reasons,
- Patients combined with malignant tumors, patients combined with psychiatric disorders.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- First Affiliated Hospital of Chongqing Medical University — Chongqing
Identifiers
NCT: NCT06730711 · 20241202