Recruiting NCT06729762
Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: ultrasound-guided thermal ablation.
- Who it may be relevant to
- Registry conditions: Thyroid Nodule (Benign). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Ultrasound-guided Thermal Ablation for the Treatment of Benign Thyroid Nodules: A Multicenter Study
Overview
To evaluate long-term outcomes of ultrasound-guided thermal ablation for benign thyroid nodules
Detailed description
To evaluate and predict long-term clinical outcomes of ultrasound-guided thermal ablation for benign thyroid nodules by a multicenter study
Interventions
- Procedure ultrasound-guided thermal ablation
radiofrequency ablation, microwave ablation, laser ablation
Primary outcome measures
- volume reduction rate [Time frame: through study completion, an average of 6 months]
Secondary outcome measures (6)
- rate of complications [Time frame: 1 week]
- cosmetic score [Time frame: through study completion, an average of 6 months]
- symptom score [Time frame: through study completion, an average of 6 months]
- rate of nodule regrowth [Time frame: through study completion, an average of 6 months]
- rate of change of thyroid function [Time frame: through study completion, an average of 6 months]
- rate of disappearance [Time frame: through study completion, an average of 6 months]
Eligibility criteria
Inclusion criteria
- confirmation of benign nodule status on two separate fine- needle aspiration or core-needle biopsy
- no suspicious malignant features on ultrasound examination
- report of cosmetic and/ or symptomatic problems or concern of nodules growing rapidly or malignant transformation
- refusal or ineligibility for surgery
- follow-up time ≥12 months
Exclusion criteria
- follicular neoplasm or malignancy findings on biopsy
- nodules with benign result on biopsy had suspicious of malignancy in US
- patients with contra-lateral vocal cord paralysis
- previous radiation to the head and neck
- follow- up time less than 12 months
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Chinese PLA General Hospital — Beijing
Identifiers
NCT: NCT06729762 · 2024-654