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Recruiting NCT06722742

Use of Iv Tramadol and Ketamine for Prevention of Post Spinal Anesthesia Shivering

Phase III Interventional Shivering, Spinal Anesthesia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Ketamine only, Tramadol.
Who it may be relevant to
Registry conditions: Shivering, Spinal Anesthesia. Basic parameters: 18 years — 40 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Pakistan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Frequency of Shivering Among Patient Treaed With IV Tramadol Versus Iv Ketamine in Prevention of Post Spinal Anesthesia Undergoing Cesarean Section: Rendomiced Control Trial

Overview

\*Ketamine:\* Ketamine is a medication that can help reduce shivering by blocking certain nerve signals in the brain. It's like a "nerve blocker" that helps calm down the body's shivering response. \- \*Tramadol:\* Tramadol is a pain medication that can also help reduce shivering. It works by affecting the brain's temperature regulation centers, which helps to reduce the shivering response.

Detailed description

Post-spinal shivering is when a patient starts shaking or shivering after receiving spinal anesthesia. This can be uncomfortable and even scary for the patient.

Using ketamine and tramadol to reduce post-spinal shivering can have several benefits, including:

* Reduced discomfort and anxiety for the patient * Improved patient satisfaction * Reduced need for additional medications or interventions * Faster recovery times

Interventions

  • Drug Ketamine only
    Inj: Ketamine given to group K following spinal anesthesia
  • Drug Tramadol
    Inj Tramadol given to group T following spinal anesthesia

Primary outcome measures

  • Shivering [Time frame: 20 minutes to 12 hours]

Eligibility criteria

Inclusion criteria

  • Pateint for elective cesarean section
  • Age 18 to 40 years
  • ASA 1 and 2

Exclusion criteria

  • ASA 2 and 3
  • Cesarean section requiring general anesthesia
  • Hypersensitivity to Ketamine, Tramadol and Opiods
  • History of cardiovascular disease

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Triple blind
Primary purpose
Treatment

Study locations

Pakistan · 3 centers
  • Liaquat National Hospital and Medical College — Karachi
  • Liaquat National Hospital and Medical College — Karachi
  • Liaquat National Hospital and Medical College — Karachi

Identifiers

NCT: NCT06722742 · #882-2023-LNH-ERC

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗