Mechanisms of Mindfulness Intervention：Rumination Behavioral Experiments
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Mindfulness Intervention for Emotional Distress(MIED)-normal version.
- Who it may be relevant to
- Registry conditions: Emotional Distress. Basic parameters: 18 years — 55 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Mechanism of Rumination in the Alleviation of Emotional Distress by Mindfulness-Based Interventions: Evidence from Behavioral Experiments
Overview
This study hopes to explore whether the changes in rumination exhibited in behavioral experiments mediates the effects of mindfulness intervention on alleviating emotional distress
Detailed description
In recent years, mindfulness-based interventions (MBIs) have seen extensive application in both clinical and non-clinical settings. Studies show that mindfulness training improves emotional regulation and processing, contributing to better emotional health. MBIs have proven effective in reducing anxiety and depression among patients with conditions like multiple sclerosis, enhancing personal well-being, and alleviating chronic pain. Given the mounting evidence supporting its benefits, MBIs have become widely adopted across various settings. Nonetheless, the precise mechanisms through which mindfulness alleviates emotional distress remain poorly understood.
Rumination, a transdiagnostic process, plays a critical role in the development and persistence of emotional distress. Empirical evidence supports the effectiveness of MBIs in reducing rumination. However, the role of rumination in mediating the effects of MBIs on emotional distress remains inconsistent across studies. Kazdin (2007, 2009) outlined criteria for evaluating mechanisms and mediators, yet existing studies lack sufficient evidence to meet these standards. This study aims to explore the mechanistic role of rumination using behavioral experiments, focusing on the consistency criterion
Interventions
- Behavioral Mindfulness Intervention for Emotional Distress(MIED)-normal version
Mindfulness Intervention for Emotional Distress (MIED) program provides standard audio instructions for mindfulness exercises, introduces the nature and law of anxiety, depression, and other emotions, the source of anxiety, depression, and other emotional distress, and the strategies and methods to alleviate emotional distress. These exercises, knowledge and strategies are based on the latest progress in the field of psychological counseling and treatment, and their application in daily life can
Primary outcome measures
- Changes of Five Facet Mindfulness Questionnaire during the intervention [Time frame: pre-intervention; week 3; week 5; immediately after the intervention]
- Changes of 10-item Kessler Psychological Distress Scale during the intervention [Time frame: pre-intervention; week 3; week 5; immediately after the intervention]
- Changes of Rumination-Reflection Questionnaire during the intervention [Time frame: pre-intervention; week 3; week 5; immediately after the intervention]
- Changes of Overall Anxiety Severity and Impairment Scale during the intervention [Time frame: pre-intervention; week 3; week 5; immediately after the intervention]
- Changes of Overall Depression Severity and Impairment Scale during the intervention [Time frame: pre-intervention; week 3; week 5; immediately after the intervention]
- Changes of the Brief State Rumination Inventory during the intervention [Time frame: pre-intervention; week 3; week 5; immediately after the intervention]
- Changes of the momentary repetitive negative thinking during the intervention [Time frame: pre-intervention; week 3; week 5; immediately after the intervention]
Eligibility criteria
Inclusion criteria
- \- Subjects with scores greater than 21 on the Kessler Psychological Distress Scale.
- \- Aged 18-55 years old.
Exclusion criteria
- \- Subjects who could not access the Internet;
- \- Subjects with insufficient Chinese ability;
- \- Subjects who have participated in mindfulness based projects for more than 6 weeks before, and / or the current frequency of meditation practice is more than once a week;
- \- Subjects with schizophrenia or psychotic affective disorder, current organic mental disorder, substance abuse disorder and generalized developmental disorder;
- \- Subjects with high risk of suicide.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Supportive care
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06722573 · E20241201