The Placental Thickness and Pregnancy Outcomes in Placenta Previa Women
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: ultrasound.
- Who it may be relevant to
- Registry conditions: Placenta Accreta. Basic parameters: 20 years — 35 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
The Third-trimester Placental Thickness and Pregnancy Outcomes in Placenta Previa Women
Overview
Placenta previa is the placenta overlying the cervical os. Placenta previa is about 1 in 200 pregnancies. The risk factors are the increasing rate of cesarean section and previous uterine surgery. Placenta previa is associated with many adverse complications; the most serious one is related to maternal hemorrhage. The diagnosis of placenta previa is done by trans-abdominal and trans-vaginal ultrasonography, which can document the placental edge's relationship to the internal os. Placenta accreta spectrum disorder is defined when trophoblastic invades the myometrium. The Placenta accreta spectrum can be categorized as: placenta accreta, placenta increta, and placenta percreta. The clinical utility of placental thickness is an area of ongoing research in placenta previa. Prior studies have demonstrated an association between mid-trimester placental thickness and placenta accreta spectrum. Despite the presence of many studies in characterizing placental thickness, most studies have focused primarily on the placental accreta spectrum lacking information about other fetal and maternal complications. Symptomatic (bleeding) placenta previa is associated with increased maternal and neonatal morbidity and mortality. In addition; the mechanism that involves bleeding is unclear. It is usually related to uterine contractions, cervical effacement, and dilation leading to separation of the placenta from the underlying decidua.
Interventions
- Other ultrasound
The placenta thickness will be performed on transabdominal images obtained in a longitudinal plane. Three measurements will be performed at the thickest portion of the placenta. The average of these three measurements was used for statistical analysis. The cohorts will be classified into 1) thick placenta (\>4 cm) and average placenta (2-4 cm).
Primary outcome measures
- number of women with placenta accreta [Time frame: 3 weeks]
Eligibility criteria
Inclusion criteria
- Pregnant women from 32-34 weeks.
- Pregnant women with singleton pregnancy.
- Women with placenta previa.
- Placenta previa with minimal vaginal bleeding or haven't any vaginal bleeding.
- Women without any medical disorders.
- Women should be living in a nearby area to make follow-up and early transportation is reasonably possible.
Exclusion criteria
- Women with severe bleeding necessitate immediate delivery.
- Women with confirmed fetal malformation.
- If associated with abruptio placentae.
- Women who will refuse to participate.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Non-randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Diagnostic
Study locations
Egypt · 1 center
- Women Health Hospital - Assiut university — Asyut
Identifiers
NCT: NCT06717997 · PAS-US