The Effect of Intraoperative Intravenous Lidocaine Infusion on Postoperative Pain and Recovery in Children (< 7 Years Old) Undergoing Thoracoscopic Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Lidocaine (drug), Saline infusion (placebo).
- Who it may be relevant to
- Registry conditions: Pain Management After Surgery. Basic parameters: 6 months — 7 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- South Korea
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Effect of Intraoperative Intravenous Lidocaine Infusion on Postoperative Pain and Recovery in Children (< 7 Years Old) Undergoing Thoracoscopic Surgery:Prospective, Randomized Controlled Trial
Overview
This study aims to investigate the efficacy of intraoperative intravenous lidocaine infusion on postoperative pain management and recovery in pediatric patients undergoing thoracoscopic pulmonary resection.
Interventions
- Drug Lidocaine (drug)
a single bolus dose of lidocaine 1.5 mg/kg is administered concurrently with the induction of anesthesia, followed by a continuous infusion of lidocaine at a rate of 1.5 mg/kg/hr. - Drug Saline infusion (placebo)
Continuous infusion of normal saline in the same volume as that administered to the lidocaine group.
Primary outcome measures
- FLACC (ace, Legs, Activity, Cry, Consolability scale) Score [Time frame: up to 1 hour after surgery]
Secondary outcome measures (5)
- Remifentanil dose [Time frame: throughout surgery (up to 3 hours)]
- ANI (Analgesia Nociception Index) [Time frame: throughout surgery (up to 3 hours)]
- FLACC scores [Time frame: 6 hours, 12 hours, and 24 hours postoperatively]
- Total analgesic dosage administered postoperatively [Time frame: up to 3 days after surgery]
- Postoperative complications [Time frame: until discharge (up to 3-4 days after surgery)]
Eligibility criteria
Inclusion criteria
- Pediatric patients aged under 7 years undergoing thoracoscopic pulmonary resection
Exclusion criteria
- cardiac dysfunction requiring vasopressors or inotropic agents
- atrioventricular block or bradycardia
- Liver or kidney dysfunction
- Hypersensitivity to local anesthetics
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Quadruple blind
- Primary purpose
- Treatment
Study locations
South Korea · 1 center
- Seoul National University Hospital — Seoul
Identifiers
NCT: NCT06710405 · H2409-100-1573