A Fast, Quiet, Artificial Intelligence-based PET/MR Solution for Paediatric Diseases
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Paediatric Patients. Basic parameters: up to 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
To investigate the feasibility of deep learning-assisted rapid silent PET/MR in pediatric applications.
Detailed description
This study aims to address the challenges faced by PET/MR in pediatric applications by leveraging new technologies such as flexible coils, silent sequences, and deep learning-based image reconstruction. The objective is to provide a rapid, silent, comfortable, and half-dose PET/MR imaging solution for pediatric patients, and to demonstrate its feasibility in this patient population.
Primary outcome measures
- Lesion detection rate [Time frame: 1 year]
- Completion of PET/MR examinations [Time frame: 1 year]
- Sedation during PET/MR examinations [Time frame: 1 year]
- Qualitative image quality [Time frame: 1 year]
Eligibility criteria
Inclusion criteria
- Children who have clinical symptoms and are suspected of having malignant tumors after being evaluated by clinical pediatricians and require 18F-FDG PET/MR examination to further clarify their conditions.
- Signed and dated informed consent form
- Commit to complying with the research procedures and cooperate in the implementation of the entire research process.
- No gender restriction, aged between 0 and 18 years old.
Exclusion criteria
- Patients with serious illnesses that researchers consider unsuitable for participation in this clinical study. Such as severe heart and lung failure, severe bone marrow suppression, severe liver and kidney dysfunction, etc.
- Patients with severe claustrophobia，epileptic seizures, respiratory distress who cannot lie down, and patients with mental anomalies who are unable to cooperate.
- Patients with metal implants such as pacemakers, artificial metal heart valves, and neurostimulators in their bodies.
- Non-compliant person.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
China · 1 center
- China, Shanghai Ruijin Hospital affiliated to Shanghai Jiao Tong University of Medicine — Shanghai
Identifiers
NCT: NCT06709690 · RuijinH 2024-467