Brain Activation Pattern Caused by Immersive Virtual Reality Pathfinding Task in Stroke Patients: an FNIRS Study
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Stroke, Cognitive Decline. Basic parameters: 18 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Brain Activation Pattern Caused by Immersive Virtual Reality Pathfinding Task in Stroke Patients: a Functional Near-infrared Spectroscopy Study
Overview
This is an fNIRS study performed to investigate Brain Activation Pattern Caused by Immersive Virtual Reality Pathfinding Task in Stroke Patients.
Detailed description
This was an initial screening and preliminary intervention study. Both healthy subject and stroke patients will be included in this study. Brain functional activation of each subject during Immersive Virtual Reality Pathfinding Task will be evaluated using functional near-infrared spectroscopy (fNIRS). Cognitive function related scale assessment included Mental State Examination Scale (MMSE), Montreal Cognitive Assessment (MoCA), drawing clock test (DCT), Shape trials test A.B (STT-A, STT-B), standardized digital modal test (SDMT), auditory verbal learning test-Huashan version (AVLT-H), and activity of daily living (ADL) scale will be used to evaluate the function of each patient. Brain Activation Pattern Caused by Immersive Virtual Reality Pathfinding Task will be identified by by comparing differences in brain activation and brain network connectivity between patients and healthy subjects.
Primary outcome measures
- Brain Activation Pattern Caused by Immersive Virtual Reality Pathfinding Task in Stroke Patients [Time frame: 1 day]
Eligibility criteria
Inclusion criteria
Stroke patients:
- Diagnosis of stroke confirmed by neuroimaging (CT or MRI)
- 18-80 years old
- Able to complete the cognitive task
- Able to follow instructions to complete the trial
- Patients who signed an informed consent form.
Healthy Subjects:
- No abnormalities on cranial
- 18-80 years old
- Able to complete cognitive task
- Able to follow instructions to complete the trial
- not taking medications.
- Subjects who signed an informed consent form.
Exclusion criteria
Stroke patients:
- Inability to tolerate the test due to organic diseases
- Serious mental illness that prevents them from cooperating with or tolerating the trial
- Pregnant or lactating women
- Had metal implants, a history of other neurological disorders, acute cardiopulmonary dysfunction.
Healthy Subjects:
- Inability to tolerate the test due to organic diseases
- Serious mental illness that prevents them from cooperating with or tolerating the trial.
- Pregnant or lactating women
- Had metal implants, a history of other neurological disorders, acute cardiopulmonary dysfunction
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-control
Study locations
China · 1 center
- Department of Rehabilitation Medicine, the First Affiliated Hospital of Chongqing Medical — Chongqing
Identifiers
NCT: NCT06703320 · 20241122