Menu
Not yet recruiting NCT06700629

Distal Hypospadias Repair Outcome

No phase Interventional Distal Penile Hypospadias (Disorder)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Distal Penile Hypospadias (Disorder).
Who it may be relevant to
Registry conditions: Distal Penile Hypospadias (Disorder). Basic parameters: from 1 year · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Preoperative Predictors of Distal Hypospadias Repair Outcome

Overview

Aim is : To define the preoperative parameters that may influence the results of distal hypospadias repair

Detailed description

Hypospadias is a congenital deformity where the opening of the urethra (the meatus) is sited on the underside (ventral) part of the penis, anywhere from the glans to the perineum.

It occurs in 1 in 250 live male births. it is often associated with "hooded" foreskin and chordee (ventral curvature of the penis shaft).

Hypospadias can be classified according to the anatomical location of meatus:

Distal-anterior hypospadias (located on the glans or distal shaft of the penis and the most common type of hypospadias) Intermediate-middle (penile). Proximal-posterior (penoscrotal, scrotal, perineal).

Diagnosis includes a description of the local findings:

Position, shape and width of the orifice Presence of atretic urethra and division of corpus spongiosum Appearance of the preputial hood and scrotum Size of the penis Curvature of the penis on erection. Aim of hypospadias surgery :(2) Is to correct penile curvature,to form neo-urethera of an adequate size, to bring the neomeatus to the tip of glans, and offer satisfactory cosmetic results.

The ideal age at surgery for primary hypospadias repair is usually 6-18 months. The complication rate is about 10% in distal hypospadias repair.

Complications include:

1. uretherocutaneous fistula. 2. meatal stenosis. 3. urethral stricture. 4. Urethral diverticulum. After hypospadias repairs, long-term follow-up is necessary, up to adolescence, to detect urethral stricture, voiding dysfunction and recurrent penile curvature.

Interventions

  • Procedure Distal Penile Hypospadias (Disorder)
    Three operations which are Tubularized incised plate urethroplasty (TIP), Mathieu and meatal advancement and glanuplasty (MAGPI). A three experienced operators with number of operations done by each one more than one hundred operation in the last year. The operators will be fixed for each surgical technique as follows: 1. Doctor (A) for Matheiu. ( 35 operations) 2. Doctor (M) for MAGPI. ( 35 operations) 3. Doctor (S) for TIP ( 35 operations). Tubularized incised plate urethroplasty:(3,6) Indi

Primary outcome measures

  • Functional outcome of Distal Penile Hypospadias Repair [Time frame: Six months postoperatively]
Secondary outcome measures (3)
  • Cosmetic outcome of Distal Penile Hypospadias Repair [Time frame: Six months postoperatively]
  • Complication Rate Following Distal Hypospadias Repair [Time frame: Weekly assessments during the first month and monthly assessments for the following five months postoperatively.]
  • Patient-Reported Outcomes [Time frame: Six months postoperatively]

Eligibility criteria

Inclusion criteria

  • Child with distal hypospadias, uncircumcised , without meatal stenosis and no previous surgery for hypospadias

Exclusion criteria

  • Any surgical manipulation includes circumcision or meatotomy. Patient refusal to be enrolled in the research. Patient lost follow up in the first six months

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Supportive care

Study locations

Egypt · 2 centers
  • Faculty Of Medicine Assiut University — Asyut
  • Noha Elabody — Asyut

Publications

  • 1) Belman AB. Hypospadias and chordee. In: Belman AB, King LR, Kramer SA, eds. Clinical Pediatric Urology. 4th edn. London, Martin Dunitz, 2002, pp. 1061-1092. 2) Mouriquand OD, Mure PY. Hypospadias. In: Gearhart J, Rink R, Mouriquand PDE, eds. Pediatric Urology, Philadelphia, WB Saunders, 2001, pp. 713-728. 3) Snodgrass W (1994) Tubularized, incised plate urethroplasty for distal hypospadias 151:

Identifiers

NCT: NCT06700629 · DPH repair outcome

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗