Exploring the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders Following Cardiovascular Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: cardiovascular surgery.
- Who it may be relevant to
- Registry conditions: Cardiovascular Surgery, Perioperative Neurocognitive Disorders. Basic parameters: from 60 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
To Explore the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders in Patients Undergoing Cardiovascular Surgery Under General Anaesthesia: a Single-centre Prospective Observational Study
Overview
To explore the predictive value of Electroencephalography features in Perioperative Neurocognitive Disorders in patients undergoing cardiovascular surgery under general anesthesia
Detailed description
Data was acquired on the ward using a 10-20 system with a standard 32-channel EEG cap and an EEG instrument (BP Company, Gilching, Germany). Patients were tested using cognitive assessment scales before and after surgery.
Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using the Montreal Cognitive Assessment (MoCA) . Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA).
Preoperative and postoperative electroencephalography brain network-related indexes (such as cluster coefficient, small world index, etc.) in patients with PND will be included in the analysis.
Interventions
- Procedure cardiovascular surgery
Heart bypass surgery; Heart valve replacement surgery
Primary outcome measures
- The predictive value of preoperative Electroencephalography features in patients with postoperative cognitive dysfunction following cardiovascular surgery [Time frame: 2025.08]
Secondary outcome measures (2)
- The predictive value of preoperative Electroencephalography features in patients with postoperative delirium following cardiovascular surgery [Time frame: 2025.08]
- Electroencephalography features in patients with postoperative delirium [Time frame: 2025.08]
Eligibility criteria
Inclusion criteria
- Written informed consent
- undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia
- ASA grade: II-IV
- older than 60 years
- Able to complete cognitive function tests
Exclusion criteria
- history of severe neurological diseases and psychiatric diseases
- history of drug abuse
- severe hearing or vision impairment
- preoperative delirium
- serious adverse reactions such as cardiac arrest and cardiopulmonary resuscitation during surgery
- patients undergoing secondary surgery in a short period
- participation in concurrent clinical trials
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Other
Study locations
China · 1 center
- Beijing Chao Yang Hospital — Beijing
Identifiers
NCT: NCT06692309 · DXK2022-ke-487