Not yet recruiting NCT06689631
Mucociliary Clearance Techniques for Acute Bronchiolitis
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Respiratory Physiotherapy.
- Who it may be relevant to
- Registry conditions: Acute Bronchiolitis Due to Respiratory Syncytial Virus, Bronchiolitis Acute, Bronchiolitis Acute Viral. Basic parameters: 28 Days — 12 months · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Efficacy of Mucociliary Clearance Techniques in Non-hospitalised Infants with Acute Bronchiolitis
Overview
To assess the efficacy of mucociliary clearance techniques in non-hospitalised infants with a first episode of mild to moderate acute bronchiolitis.
Interventions
- Procedure Respiratory Physiotherapy
Mucociliary clearance techniques (prolonged slow expiration and provoked cough), bronchodilator when prescribed and nebulisation with 3% hypertonic saline.
Primary outcome measures
- ESBA [Time frame: 1 session (45 minutes)]
Eligibility criteria
Inclusion criteria
- Medical diagnosis of first episode of acute Bronchiolitis.
- Acute Bronchiolitis with mild (ESBA score = 1-4) or moderate (ESBA score =5-9) severity according to the ESBA.
- Informed consent signed by parents or legal guardians.
Exclusion criteria
- Infants previously diagnosed with chronic respiratory disease.
- Previous episodes of wheezing.
- Presence of any type of contraindication to receive Respiratory Physiotherapy treatment.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Gonzalez Bellido V, Velaz Baza V, Esteo MDCJ, Carballo RG, Colombo A, Zaldivar JNC, Donadio MVF. Safety of airway clearance combined with bronchodilator and hypertonic saline in non-hospitalized infants with acute bronchiolitis. Arch Pediatr. 2021 Nov;28(8):707-711. doi: 10.1016/j.arcped.2021.09.007. Epub 2021 Oct 5. PMID 34625378
Identifiers
NCT: NCT06689631 · ETICA-ULE-062-2023 · ULE