Effect of Smoking Cessation on Glycemic Control in Type 2 Diabetics
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Smoking cessation counselling group.
- Who it may be relevant to
- Registry conditions: Smoking Cessation. Basic parameters: 35 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effect of Smoking Cessation on Glycemic Control in Patients with Type 2 Diabetes
Overview
The goal of this observational study is to learn about the long-term effects of smoking cessation on glycemic control in type 2 diabetic patients The main question it aims to answer is: Does smoking cessation lower HbA1c in type 2 diabetics on long term ? The participants will be counseled to cessate smoking and will be followed for 6 months and compared to control who will not cessate smoking .
Detailed description
Smoking and diabetes are both major public health issues specially in our community. They act synergistically on morbidity and mortality. Diabetic smokers have much higher rates of micro and macrovascular complications. \[Carole Clair et al., 2020\] Approximately 1.3 billion people worldwide use tobacco, most commonly in the form of tobacco smoking, and more than 7 million people die every year as a result of smoking related conditions \[Magdalena Walicka et al.,2022\] Exposure to cigarette smoke is associated with vascular damage, endothelial dysfunction, and activation of oxidative stress, inflammatory pathways, coagulation, and fibrinolysis A similar mechanism of endothelial dysfunction is described for people with diabetes. It is therefore not surprising that smoking enhances the combined harmful effects of elevated blood glucose levels, accelerating vascular damage in diabetic patients who smoke The prevalence of current smoking was 45.5% in male patients with type 2 diabetes. The levels of fasting blood glucose and HbA1c increased with number of cigarettes smoked per day compared with non-smokers Smoking and its cessation showed dose- and time-dependent relationship with glycemic control and insulin resistance in patients with type 2 diabetes mellitus. These findings may highlight the importance of smoking cessation in the clinical management of diabetes mellitus.
the effect of smoking and its cessation on glycemic control in diabetic patients has not been fully examined yet.
There is lack of evidence regarding interventions for smoking cessation among individuals with diabetes
Interventions
- Behavioral Smoking cessation counselling group
Case group will be counseled to cessate smoking and will be followed up with HbA1c
Primary outcome measures
- Glycemic control after smoking cessation [Time frame: 6 months]
Eligibility criteria
Inclusion criteria
\- Moderate Somking index Having been diagnosed with a type 2 diabetes Being ≥ 35 years old HbA1c > 7
Exclusion criteria
Type 1 diabetes Drug induced Diabetes mellitus Type 2 diabetes on insulin treatment
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-control
Study locations
Egypt · 1 center
- Assuit university — Asyut
Identifiers
NCT: NCT06687213 · Smoking cessation and HbA1C