Comparative Effects of Sensory Re-education and Neural Mobilization in CTS Patients
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Sensory re-education+ strengthening exercises+ kinesio taping, Neural mobilization+ Strengthening exercises+ Kinesio taping..
- Who it may be relevant to
- Registry conditions: Carpal Tunnel Syndrome (CTS). Basic parameters: 20 years — 50 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Comparative Effects of Sensory Re-education and Neural Mobilization in Carpal Tunnel Syndrome Patients
Overview
The aim of study is to compare the effects of sensory re-education and neural mobilization in CTS patients.
Detailed description
This study will be randomized clinical trial that will be conducted at Services Hospital Lahore and Government Teaching Hospital Shahdara. In this study 48 participants with CTS will be included as per sample size calculation through non-probability convenience sampling technique. Participants that achieve the required standards of inclusion and exclusion criteria will be randomly allocated using online randomization tool into two groups. Group A will receive Sensory Re-education therapy, strengthening exercises and Kinesio taping for 60 minutes, Group B will be given neural mobilization techniques, strengthening exercises and Kinesio taping for 60 minutes with short rest intervals. Both treatments will be given 3 days per week for 12 weeks.
Interventions
- Other Sensory re-education+ strengthening exercises+ kinesio taping
Sensory re-education. Splinting: as constant maintained touch with wrist holding in neutral position for 15 minutes. Topical anesthesia spray on affected area for 10 minutes. Massage: apply massage over sensitive areas with same speed and pressure, then the light pressure with cotton, velvet, terry cloth, polyester and wool over sensitive area for 10 minutes. PNF using upper extremity (D2) pattern including shoulder extension, adduction, internal rotation, wrist and fingers flexed and wrist ul - Other Neural mobilization+ Strengthening exercises+ Kinesio taping.
The median nerve is mobilized through wrist flexion and extension with elbow straight and palm facing up. Wrist flexion and extension with elbow flexed to 90 degrees with palm facing up 10-15 repetitions. Wrist flexors stretch with extended arm and palm facing down 10-15 repetitions. Straight fist: hold your hand up with fingers straight. Full fist: bend your fingers to form a full fist. Median nerve stretch and wrist extension exercises for 30 minutes. Free the bird exercises, busy bee flexio
Primary outcome measures
- Numerical pain rating scale [Time frame: 12th week]
- Boston Carpal Tunnel Questionnaire [Time frame: 12th week]
- Hand Held Dynamometer [Time frame: 12th week]
- Pinch gauge meter [Time frame: 12th week]
Eligibility criteria
Inclusion criteria
- Patients of both genders age 20-50 years with mild and moderate carpal tunnel syndrome.
- Patients having positive score on CTS specific test (Phalen's test and Tinel's test).
- Patients with pain, paresthesia and hyperesthesia at the course of median nerve.
- Patients that are clinically diagnosed with carpal tunnel syndrome by physician. Patients having BMI >25 (kg/m2).
Exclusion criteria
- Patients with polyneuropathies.
- Patients with carpal tunnel syndrome due to any systemic illness (diabetes mellitus, thyroid diseases and R.A).
Patients having cervical radiculopathy.
Patients with history of wrist fracture.
Patients getting steroid injections and after CTS surgery.
Obese and pregnant female with carpal tunnel syndrome.
Patients with any cognitive or neurological problems are excluded from study.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Sheereen FJ, Sarkar B, Sahay P, Shaphe MA, Alghadir AH, Iqbal A, Ali T, Ahmad F. Comparison of Two Manual Therapy Programs, including Tendon Gliding Exercises as a Common Adjunct, While Managing the Participants with Chronic Carpal Tunnel Syndrome. Pain Res Manag. 2022 Jun 8;2022:1975803. doi: 10.1155/2022/1975803. eCollection 2022. PMID 35719196
- Jimenez-Del-Barrio S, Cadellans-Arroniz A, Ceballos-Laita L, Estebanez-de-Miguel E, Lopez-de-Celis C, Bueno-Gracia E, Perez-Bellmunt A. The effectiveness of manual therapy on pain, physical function, and nerve conduction studies in carpal tunnel syndrome patients: a systematic review and meta-analysis. Int Orthop. 2022 Feb;46(2):301-312. doi: 10.1007/s00264-021-05272-2. Epub 2021 Dec 3. PMID 34862562
- Hassan A, Beumer A, Kuijer PPFM, van der Molen HF. Work-relatedness of carpal tunnel syndrome: Systematic review including meta-analysis and GRADE. Health Sci Rep. 2022 Nov 2;5(6):e888. doi: 10.1002/hsr2.888. eCollection 2022 Nov. PMID 36340637
- Abdolrazaghi HA, Khansari M, Mirshahi M, Ahmadi Pishkuhi M. Effectiveness of Tendon and Nerve Gliding Exercises in the Treatment of Patients With Mild Idiopathic Carpal Tunnel Syndrome: A Randomized Controlled Trial. Hand (N Y). 2023 Mar;18(2):222-229. doi: 10.1177/15589447211006857. Epub 2021 Apr 15. PMID 33855879
- Lam NW, Goh HT, Kamaruzzaman SB, Chin AV, Poi PJ, Tan MP. Normative data for hand grip strength and key pinch strength, stratified by age and gender for a multiethnic Asian population. Singapore Med J. 2016 Oct;57(10):578-584. doi: 10.11622/smedj.2015164. Epub 2015 Nov 13. PMID 26768064
- Almasi-Doghaee M, Boostani R, Saeedi M, Ebrahimzadeh S, Moghadam-Ahmadi A, Saeedi-Borujeni MJ. Carpal compression, Phalen's and Tinel's test: Which one is more suitable for carpal tunnel syndrome? Iran J Neurol. 2016 Jul 6;15(3):173-4. No abstract available. PMID 27648179
- Du J, Yuan Q, Wang XY, Qian JH, An J, Dai Q, Yan XY, Xu B, Luo J, Wang HZ. Manual Therapy and Related Interventions for Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis. J Integr Complement Med. 2022 Dec;28(12):919-926. doi: 10.1089/jicm.2022.0542. Epub 2022 Jul 27. PMID 35895497
- Ijaz MJ, Karimi H, Ahmad A, Gillani SA, Anwar N, Chaudhary MA. Comparative Efficacy of Routine Physical Therapy with and without Neuromobilization in the Treatment of Patients with Mild to Moderate Carpal Tunnel Syndrome. Biomed Res Int. 2022 Jun 22;2022:2155765. doi: 10.1155/2022/2155765. eCollection 2022. PMID 35782066
Identifiers
NCT: NCT06686212 · REC/RCR&AHS/24/0233