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Recruiting NCT06685523

Evaluation of Fractalkine and Its Receptor in Peri-implantitis

No phase Interventional Peri-implantitis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Subgingival debridement, Er:YAG laser decontamination, Diyot laser decontamination.
Who it may be relevant to
Registry conditions: Peri-implantitis. Basic parameters: 40 years — 60 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Evaluation of Fractalkine and Its Receptor in the Non-Surgical Treatment of Peri-implantitis

Overview

In this study, mechanical debridement group, Er:YAG laser group and diode laser group will be compared in terms of reducing peri-implant sulcus depth in the treatment of peri-implantitis.

Interventions

  • Procedure Subgingival debridement
    To be applied 1 times (0. days)
  • Procedure Er:YAG laser decontamination
    To be applied 3 times
  • Procedure Diyot laser decontamination
    To be applied 3 times

Primary outcome measures

  • Probing depth, clinical attachment loss [Time frame: sixth month]
Secondary outcome measures (1)
  • gingival index, plaque index, sulcus blood index [Time frame: sixth month]

Eligibility criteria

Inclusion criteria

  • Probing depth of 4-6 mm, bone loss of at least 2 mm on X-ray and presence of inflammatory symptoms in soft tissue
  • No systemic disease that may affect the outcome of the treatment
  • Patients with healthy periodontium or patients with completed periodontal treatment
  • Individuals at least 6 months after prosthesis loading on the implant
  • Individuals who do not require further surgery for the treatment of peri-implantitis
  • Implants with at least 2 mm keratised gingiva
  • Individuals aged 40-60 years

Exclusion criteria

  • Individuals undergoing radiation therapy
  • Individuals who smoke and drink alcohol
  • Individuals in pregnancy or lactation
  • Individuals who have received antibiotic treatment in the last three months
  • Individuals with parafunctional habits

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Turkey (Türkiye) · 1 center
  • Kırıkkale University, Faculty of Dentistry, Department of Periodontology — Kirikkale

Identifiers

NCT: NCT06685523 · KU-DHF-KB-01

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗