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Recruiting NCT06685497

COLORECTUM+ Digital System for Postoperative Quality Improvement in Colorectal Cancer

No phase Interventional Colorectal Carcinoma

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Mobile application follow-up.
Who it may be relevant to
Registry conditions: Colorectal Carcinoma. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Construction and Application of a Digital Postoperative Medical Quality Evaluation and Promotion System for Colorectal Cancer Based on the COLORECTUM+ Model

Overview

This is a single-center, prospective, interventional study. A total of 236 colorectal cancer patients who underwent surgery will be enrolled and followed for 52 weeks. The digital healthcare quality management system, based on the COLORECTUM+ model, will be used for post-treatment quality evaluation and continuous improvement. Patients will be managed using an Internet+ post-treatment healthcare management platform. The platform integrates AI technology for real-time symptom analysis and alerts. Patients will report symptoms and health data through the platform, which will generate alerts based on symptom severity to guide appropriate interventions. Follow-up assessments will include patient adherence, satisfaction, quality of life, and healthcare utilization. The study expects to demonstrate that the digital healthcare quality management system improves follow-up rates, enhances patient adherence, reduces unplanned hospital visits, and increases overall patient satisfaction. The findings aim to provide evidence for the implementation of digital management systems in colorectal cancer post-treatment care, potentially leading to improved long-term outcomes for patients.

Detailed description

The aim of this study is to evaluate the adherence of postoperative colorectal cancer patients using a digital follow-up platform. The primary endpoint is follow-up rate at 3 months after surgery. The secondary endpoints are: follow-up rate at 6, 9, and 12 months, adherence during 12 months, medication adherence (MMS-4), the number and reasons for alerts triggered by patients, the frequency and reasons for patient-initiated report, quality of life (FACT-C), patient satisfaction (FACIT-TS-PS), the system's usability (SUS), the monitoring rates of imaging exams, colonoscopies, and CEA markers at 3, 6, 9, and 12 months will be analyzed. Differences in clinical outcomes: progression-free survival, overall survival, adverse events, the incidence of complications, hospital admissions (unplanned hospital visit rates, average unplanned hospital stay duration, and potentially preventable emergency visits) are additional outcomes.

Interventions

  • Device Mobile application follow-up
    Colorectal cancer patients enrolled in the 'Internet Plus' post-treatment management platform use the digital medical quality management system based on the 'COLORECTUM+' model for quality evaluation and continuous improvement. The platform integrates AI, using natural language processing and machine learning to analyze patient-reported symptoms, automatically assess severity, and generate alerts. Alerts are classified as yellow, orange, or red. Yellow indicates mild issues with self-care recomm

Primary outcome measures

  • three-month follow-up rate [Time frame: At 12 weeks after enrollment.]
Secondary outcome measures (9)
  • adherance [Time frame: From enrollment to the end of treatment at 52 weeks, patient adherence will be assessed at each visit.]
  • Quality of life [Time frame: From enrollment to the end of treatment at 52 weeks]
  • Average unplanned hospitalization days [Time frame: The 3rd, 6th, 9th, and 12th months after enrollment]
  • Potentially preventable emergency department visits [Time frame: The 3rd, 6th, 9th, and 12th months after enrollment]
  • Number and distribution of alerts [Time frame: The 3rd, 6th, 9th, and 12th months after enrollment]
  • Number and distribution of proactive reports [Time frame: The 3rd, 6th, 9th, and 12th months after enrollment]
  • Patient satisfaction [Time frame: At the end of patient follow-up]
  • System usability of the digital health quality management system [Time frame: The 3rd and 12th months after enrollment]
  • Nutritional status [Time frame: From enrollment to the end of treatment at 52 weeks]

Eligibility criteria

Inclusion criteria

  • Over 18 years old.
  • Pathologically confirmed colorectal cancer patients.
  • Underwent surgery at the Colorectal Cancer Diagnosis and Treatment Center, Gastrointestinal Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine.
  • Signed informed consent form.

Exclusion criteria

  • Unable to access electronic devices that can connect to the internet or mobile communications.
  • Uncontrolled psychiatric illness.
  • The ECOG score is greater than or equal to 3.
  • Deemed unsuitable for participation by the investigator.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Other

Study locations

China · 1 center
  • Shanghai Jiao Tong University School of Medicine, Renji Hospital — Shanghai

Identifiers

NCT: NCT06685497 · LY2024-208-B

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗