Acceptability, Usability and Preliminary Effectiveness of ChatGPT in Increasing Seasonal Influenza Vaccination Uptake Among Older Adults in Hong Kong
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Access to a trained ChatGPT.
- Who it may be relevant to
- Registry conditions: Behavior Change Interventions. Basic parameters: from 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
In this project, we will train a ChatGPT to provide real-time answers to questions related to the SIV for older adults in Hong Kong. This study aims to evaluate the usability, acceptability, and preliminary effectiveness of the ChatGPT among 50 community-living people aged 65 years and above in Hong Kong. The primary objectives are to evaluate the usability and acceptability (including the extent of usage and subjective experiences of behavioural, cognitive, and affective engagement) of the ChatGPT at the end of the 4-week intervention period (T1). The secondary objectives are to evaluate the following conditions measured at T1, as compared to those measured at baseline (T0): 1. Self-reported uptake of SIV in the past month. 2. Changes in behavioural intention to receive SIV for the approaching flu season. 3. Changes in knowledge and attitudes related to SIV.
Interventions
- Behavioral Access to a trained ChatGPT
Participants will be invited to use a trained ChatGPT which answers questions related to seasonal influenza vaccination. The functions can be used repeatedly throughout the intervention period (4 weeks), and participants will be free to spend as much time as they want on such functions.
Primary outcome measures
- Perceived usability [Time frame: 1 month]
- Extent of usage documented by the ChatGPT [Time frame: 1 month]
- Subjective experiences related to behavioural, cognitive, and affective engagement [Time frame: 1 month]
Eligibility criteria
Inclusion criteria
- Aged ≥65 years;
- Possession of a Hong Kong ID;
- Able to speak and comprehend Cantonese;
- Have a smartphone with internet access;
- Have not taken SIV for the approaching flu season.
Exclusion criteria
- With diagnosis of cognitive impairment or dementia;
- Either blindness or deafness;
- With known contraindications to the SIV as indicated by the Hong Kong Centre for Health Protection
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Health services research
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Wang Z, Tsang TH, Yu FY, Fang Y, Chen S, Sun F, Mo PKH, Wong KC. Effectiveness, Usability, and Acceptability of ChatGPT With Retrieval-Augmented Generation (SIV-ChatGPT) in Increasing Seasonal Influenza Vaccination Uptake Among Older Adults: Quasi-Experimental Study. J Med Internet Res. 2025 Sep 8;27:e76849. doi: 10.2196/76849. PMID 40921067
Identifiers
NCT: NCT06679647 · SIV_ChatGPT