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Recruiting NCT06669897

Validation of a Questionnaire to Measure Cough Severity

Observational Cough

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Questionnaire.
Who it may be relevant to
Registry conditions: Cough. Basic parameters: 30 years — 99 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Spain
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Validation of a Questionnaire to Measure Cough Severity in Patients With Chronic Cough

Overview

To design and validate a questionnaire that allows objective assessment of the severity of chronic cough

Detailed description

Chronic cough is a common disease that has important consequences for patients, ranging from physical to psychological and social aspects. However, there is currently no tool to objectively validate cough severity.

The aim of the study is to design and validate a questionnaire to objectively assess the severity of chronic cough.

Interventions

  • Other Questionnaire
    Chronic cough questionnaire

Primary outcome measures

  • A questionnaire for assessing the severity of chronic cough [Time frame: 1 year]
Secondary outcome measures (1)
  • Correlation of the results of the questionnaire with frequency of cough [Time frame: 1 year]

Eligibility criteria

Inclusion criteria

  • Aged between 30 and 99 years
  • Clinical diagnosis of chronic cough or healthy volunteers
  • Good understanding of Spanish

Exclusion criteria

  • Non-Spanish-speaking patients
  • Inability to complete the questionnaires
  • Failure to sign the informed consent form

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Other

Study locations

Spain · 6 centers
  • Hospital Universitario Hermanos Trias y Pujol — Badalona
  • Hospital Univesitario de Bellvitge — L'Hospitalet de Llobregat
  • Parc Taulí Hospital Universitari — Sabadell
  • Hospital del Mar — Barcelona
  • Hospital Clínic de Barcelona — Barcelona
  • Hospital de la Santa Creu i Sant Pau. Carrer Mas Casanovas 90. — Barcelona

Publications

  • French CT, Irwin RS, Fletcher KE, Adams TM. Evaluation of a cough-specific quality-of-life questionnaire. Chest. 2002 Apr;121(4):1123-31. doi: 10.1378/chest.121.4.1123. PMID 11948042
  • McGarvey L, Gibson PG. What Is Chronic Cough? Terminology. J Allergy Clin Immunol Pract. 2019 Jul-Aug;7(6):1711-1714. doi: 10.1016/j.jaip.2019.04.012. Epub 2019 Apr 17. PMID 31002958
  • Morice AH, McGarvey LP, Dicpinigaitis PV. Cough hypersensitivity syndrome is an important clinical concept: a pro/con debate. Lung. 2012 Feb;190(1):3-9. doi: 10.1007/s00408-011-9351-y. Epub 2011 Dec 22. PMID 22186805
  • Haque RA, Usmani OS, Barnes PJ. Chronic idiopathic cough: a discrete clinical entity? Chest. 2005 May;127(5):1710-3. doi: 10.1378/chest.127.5.1710. PMID 15888850
  • Song WJ, Chang YS, Faruqi S, Kim JY, Kang MG, Kim S, Jo EJ, Kim MH, Plevkova J, Park HW, Cho SH, Morice AH. The global epidemiology of chronic cough in adults: a systematic review and meta-analysis. Eur Respir J. 2015 May;45(5):1479-81. doi: 10.1183/09031936.00218714. Epub 2015 Feb 5. No abstract available. PMID 25657027
  • Morice A. Chronic cough: epidemiology. Chron Respir Dis. 2008;5(1):43-7. doi: 10.1177/1479972307084252. PMID 18303101
  • Irwin RS, Baumann MH, Bolser DC, Boulet LP, Braman SS, Brightling CE, Brown KK, Canning BJ, Chang AB, Dicpinigaitis PV, Eccles R, Glomb WB, Goldstein LB, Graham LM, Hargreave FE, Kvale PA, Lewis SZ, McCool FD, McCrory DC, Prakash UBS, Pratter MR, Rosen MJ, Schulman E, Shannon JJ, Hammond CS, Tarlo SM. Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidel PMID 16428686

Identifiers

NCT: NCT06669897 · IIBSP-TOS-2023-133

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗