Erythropoietin Gel Effect on Dental Implant Stability
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Non coated dental implants, Erythropoietin gel coated implants.
- Who it may be relevant to
- Registry conditions: Osseointegration. Basic parameters: 20 years — 50 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Evaluation of Erythropoietin Gel Effect on Stability of Immediate Implant ( Clinical and Radiographical Study )
Overview
* Achieving and maintaining long-term osseointegration for dental implants is a key objective in the field of dentistry. The success of osseointegration is influenced by the surface treatment applied to dental implants. Numerous coating techniques have been developed to improve and speed up osseointegration. * The aim of the current study is to assess immediate dental implant stability coated with erythropoietin gel, both clinically and radiographically. * Materials and Methods: We conducted a randomized controlled clinical trial.The sample will include patients demanding immediate implant treatment in the anterior maxilla . Patients will be randomly allocated into the two groups of the study. The group A will be treated with erythropoietin gel coated dental implant immediately after extraction of non restorable teeth in the anterior maxilla . Group B will be treated with non coated dental implant immediately after extraction of non restorable teeth in the anterior maxilla . * The primary outcome variable will be implant stability and the secondary outcome will be crestal marginal bone level and bone density around implants. It will be measured at time of implant placement and reevaluated after 6-months .
Interventions
- Other Non coated dental implants
Patients with fresh extraction sockets in the anterior maxilla will be treated by non coated immediate implant . - Other Erythropoietin gel coated implants
Patients with fresh extraction sockets in the anterior maxilla will be treated by immediate implant coated by erythropoietin gel.
Primary outcome measures
- Change in implant stability [Time frame: Baseline and after 6 month]
Secondary outcome measures (1)
- Change in marginal bone level and bone density around implants [Time frame: Baseline and after 6 month]
Eligibility criteria
Inclusion criteria
- All patients Should have nonrestorable teeth in the anterior maxilla indicated for extraction and seeking implant placement.
- Good general periodontal health and maintenance.
Exclusion criteria
- Heavy smokers who smoke more than ten cigarettes per day
- Acute infected socket
- Ant socket with wall defect.
- Pregnency
- Local or systemic conditions that will interfere with bone healing (uncontrolled diabetes mellitus or human immune deficiency virus infections, resonance therapy), bone disorders (hyperparathyroidism, osteoporosis, or Paget's disease.
- Patients who had subjected to intravenous and/or oral bisphosphonate therapy.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Faculty of dental medicine Al-Azhar university — Asyut
Identifiers
NCT: NCT06665451 · Implant surface modification