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Not yet recruiting NCT06664073

Heart Risk 6 Scale in Emergency Department Acute Heart Failure Patients

— Observational Acute Heart Failure (AHF)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Acute Heart Failure (AHF). Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

The Predictive Value of the HEARTRISK6 Scale in Predicting Short-Term Serious Outcomes in Emergency Department Acute Heart Failure Patients

Overview

Detect the predictive value of the HEARTRISK6 Scale in Predicting Short-Term Serious Outcomes in emergency department acute heart failure patients in Egyptian population

Detailed description

Recently, the heartrisk6 scale was introduced to predict the short-term serious outcomes in emergency department acute heart failure patients. It was created from 3 cohorts from American and Canadian population. Since the Egyptian population differ from the American and Canadian population regarding the age at presentation with cardiovascular disease, risk factors and etiology of the acute heart failure, we sought to detect the applicability of this score on our population.

Primary outcome measures

  • Detect the predictive value of the heart risk 6 scale [Time frame: 1 month]
Secondary outcome measures (1)
  • Describe the management and outcomes of ED patients with acute heart failure [Time frame: 1]

Eligibility criteria

Inclusion criteria

  • patients who have appropriate symptoms (short-ness of breath or fatigue)(<7 days duration); with clinical signs of fluid retention (pulmonary or peripheral) in the presence of an underlying abnormality of cardiac structure or function.
  • If in doubt, a beneficial response to treatment (eg, a brisk diuresis accompanied by improvement in breathlessness) will be considered.

Exclusion criteria

  • Patients who did not fit the definition of AHF or who were clearly too ill to be considered for discharge after 24 hours from ED:
  • 1\) resting oxygen saturation <85% on room air
  • 2\) heart rate >120 beats/min;
  • 3\) systolic blood pressure <85 mm Hg;
  • 4\) confusion, disorientation, dementia;
  • 5\) primary presentation for ischemic chest pain requiring treatment or with acute ischemic ST-Tchanges on initial electrocardiogram (ECG);

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Center list to be confirmed — check the primary protocol.

Publications

  • Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS, Falk V, Gonzalez-Juanatey JR, Harjola VP, Jankowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GMC, Ruilope LM, Ruschitzka F, Rutten FH, van der Meer P; ESC Scientific Document Group. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the PMID 27206819
  • Stiell IG, Clement CM, Brison RJ, Rowe BH, Borgundvaag B, Aaron SD, Lang E, Calder LA, Perry JJ, Forster AJ, Wells GA. A risk scoring system to identify emergency department patients with heart failure at high risk for serious adverse events. Acad Emerg Med. 2013 Jan;20(1):17-26. doi: 10.1111/acem.12056. PMID 23570474
  • Stiell IG, Perry JJ, Eagles D, Yadav K, Clement CM, McRae AD, Yan JW, Mielniczuk L, Rowe BH, Borgundvaag B, Dreyer J, Brown EL, Nemnom MJ, Taljaard M. The HEARTRISK6 Scale: Predicting Short-Term Serious Outcomes in Emergency Department Acute Heart Failure Patients. JACC Adv. 2024 May 24;3(7):100988. doi: 10.1016/j.jacadv.2024.100988. eCollection 2024 Jul. PMID 39129980

Identifiers

NCT: NCT06664073 · Heart Risk 6 scale in HF

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗