Effect of Practicing Yoga and Meditation on Cortisol Hormone, Immunoglobulin A and Metabolic Parameter Among Medical Students
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: GSY Yoga Intervention.
- Who it may be relevant to
- Registry conditions: Healthy, Adult Children. Basic parameters: 18 years — 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Hungary
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This clinical trial aims to develop and test a yoga intervention to improve cortisol hormone rhythm, immunoglobulin A, and metabolic markers among medical students. The development of the yoga protocol, "GSY Goodbye Stress with Yoga Proto-col," was a collaborative effort involving a certified yoga trainer, medical researcher, and experienced yogis from India. GSY yoga intervention, which includes yoga asanas poses, breathing techniques, and guided meditation, may reduce stress levels, improve immunity, and enhance other metabolic parameters in medical students.
Detailed description
PRIMARY OBJECTIVE:
1. To examine the effectiveness of yoga intervention as a stress reduction technique and measure its effects on the level of cortisol, immunoglobulin A (IgA), and metabolic parameters. 2. To Compare the outcomes of a yoga intervention group to a non-yoga intervention group to determine whether practicing yoga can reduce the negative impacts of elevated cortisol on the physiological parameters.
SECONDARY OBJECTIVES:
1. To determine the correlation between the psychophysiological stress and cortisol hormone in students. 2. To investigate the effect of yoga intervention on student mental health and well-being.
OUTLINE:
Participants receive yoga intervention from a certified yoga trainer once a week for 10 weeks.
Interventions
- Behavioral GSY Yoga Intervention
In the GSY yoga intervention, where participants received 90 minutes/week yoga intervention for duration of 10 weeks.
Primary outcome measures
- Effect of GSY Yoga Intervention in the Improvement of Immunoglobulin A among Medical Students [Time frame: upto 10 weeks]
- Efficacy of GSY yoga intervention in the reduction of cortisol hormone rhythm [Time frame: upto 10 weeks]
- Efficacy of GSY yoga intervention in the cortisol hormone by using hair cortisol concentration [Time frame: 10 weeks]
- Effect of 10 weeks yoga intervention on immune and metabolic parameter among medical students [Time frame: Upto 10 weeks]
Secondary outcome measures (6)
- Changes in Quality of life [Time frame: upto 10 weeks]
- Changes in sleep quality [Time frame: upto 10 weeks]
- Changes in physical activity [Time frame: upto 10 weeks]
- Changes in stress reduction [Time frame: upto 10 weeks]
- Changes in emotional regulation [Time frame: upto 10 weeks]
- Changes in Sedentary Behaviour [Time frame: Upto 10 weeks]
Eligibility criteria
Inclusion criteria
The inclusion criteria for the study required participants to be currently enrolled in the Medicine Faculty of the University of Pecs
Exclusion criteria
Students with illnesses (such as recent injuries, chronic pain, or significant arthritis) that would make it unsafe for them to take part in a yoga intervention will be excluded from the study.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Non-randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Prevention
Study locations
Hungary · 1 center
- University of Pécs — Pécs
Publications
- Chauhan S, Babu AM, Galgalo DA, Melczer C, Premusz V, Karsai I. Effect of yoga in medical students to reduce the level of depression, anxiety, and stress: pilot study (Goodbye Stress with Yoga GSY). BMC Complement Med Ther. 2024 May 24;24(1):203. doi: 10.1186/s12906-024-04496-0. PMID 38790041
- Chauhan S, Najaf SS, Nagy Z, Al-Jawarneh M, Nagy T, Miseta A, Premusz V, Karsai I. An exploratory study on the changes in immune and metabolic parameters by 10 weeks of yoga intervention among medical students. Sci Rep. 2025 Nov 5;15(1):38730. doi: 10.1038/s41598-025-22421-4. PMID 41193511
- Chauhan S, Najaf SS, Lukacs G, Kinga KA, Karsai I, Premusz V. Impact of 10 Weeks of Yoga Intervention on Mental Health and Overall Well-Being Among Medical Students: GSY Study. Sports (Basel). 2025 Apr 10;13(4):114. doi: 10.3390/sports13040114. PMID 40278740
Identifiers
NCT: NCT06661603 · GSY (Goodbye Stress with Yoga)