Erector Spinae Plane Block with Dexmedetomidine and Bupivacain Versus Dexamethasone and Bupivacain for Postoperative Analgesia in Patients Undergoing Abdominal Surgeries
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Erector Spinae Plane Block.
- Who it may be relevant to
- Registry conditions: Analgesia, Postoperative. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
To compare the analgesic effect of dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries
Interventions
- Procedure Erector Spinae Plane Block
dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries.
Primary outcome measures
- VAS score [Time frame: at 30 minutes, 2, 4, 6, 8, 12, 16, 20, and 24 hours postoperative.]
Secondary outcome measures (1)
- the time for requirement of first morphine dose [Time frame: at 30 minutes, 2, 4, 6, 8, 12, 16, 20, and 24 hours postoperative.]
Eligibility criteria
Inclusion criteria
Age :18 years old and older. Patients undergoing open abdominal surgery.
Exclusion criteria
- Patient refusal
- known sensitivity or contraindication to any of study drugs
- contraindications for local anesthesia
- Patients with local infection at site of puncture
- uncooperative patients
- history of psychological disorders or chronic pain and significant liver or renal disease.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Prevention
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Gottschalk A, Durieux ME, Nemergut EC. Intraoperative methadone improves postoperative pain control in patients undergoing complex spine surgery. Anesth Analg. 2011 Jan;112(1):218-23. doi: 10.1213/ANE.0b013e3181d8a095. Epub 2010 Apr 24. PMID 20418538
Identifiers
NCT: NCT06658418 · erector spinae plane block