Recruiting NCT06655012
Salmeterol Effect on Exercise Performance
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Salmeterol, Placebo.
- Who it may be relevant to
- Registry conditions: Healthy. Basic parameters: 18 years — 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Denmark
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
The Muscle Anabolic Response to β2-adrenergic Stimulation
Overview
The purpose of the project is to investigate the muscle anabolic response to acute beta2-adrenergic stimulation in young healthy men and women.
Interventions
- Drug Salmeterol
Participants are administered 200 µg salmeterol (8 puffs) from a MDI device - Drug Placebo
Participants are administered placebo (8 puffs) from a MDI device
Primary outcome measures
- Power output during sprint testing [Time frame: Through study completion, an average on 2 weeks]
Secondary outcome measures (1)
- Power output during time trial [Time frame: Through study completion, an average on 2 weeks]
Eligibility criteria
Inclusion criteria
- Inclusion Criteria:
- Age 18-40
- Physically active >5 hours a week
- Maximum oxygen uptake classified as high or very high
Exclusion criteria
- Active smoker currently or within the past 5 years
- Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women)
- Chronic or acute illness deemed by the responsible study physician to affect the test parameters
- Deviation from the study protocol
- Lean mass index >21 kg/m²
- Pregnancy
- Smoker
- Blood donation during the past 3 months
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Crossover
- Masking
- Quadruple blind
- Primary purpose
- Basic science
Study locations
Denmark · 1 center
- August Krogh Building — Copenhagen
Identifiers
NCT: NCT06655012 · SALM_acute