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Recruiting NCT06655012

Salmeterol Effect on Exercise Performance

No phase Interventional Healthy

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Salmeterol, Placebo.
Who it may be relevant to
Registry conditions: Healthy. Basic parameters: 18 years — 40 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Denmark
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Muscle Anabolic Response to β2-adrenergic Stimulation

Overview

The purpose of the project is to investigate the muscle anabolic response to acute beta2-adrenergic stimulation in young healthy men and women.

Interventions

  • Drug Salmeterol
    Participants are administered 200 µg salmeterol (8 puffs) from a MDI device
  • Drug Placebo
    Participants are administered placebo (8 puffs) from a MDI device

Primary outcome measures

  • Power output during sprint testing [Time frame: Through study completion, an average on 2 weeks]
Secondary outcome measures (1)
  • Power output during time trial [Time frame: Through study completion, an average on 2 weeks]

Eligibility criteria

Inclusion criteria

  • Inclusion Criteria:
  • Age 18-40
  • Physically active >5 hours a week
  • Maximum oxygen uptake classified as high or very high

Exclusion criteria

  • Active smoker currently or within the past 5 years
  • Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women)
  • Chronic or acute illness deemed by the responsible study physician to affect the test parameters
  • Deviation from the study protocol
  • Lean mass index >21 kg/m²
  • Pregnancy
  • Smoker
  • Blood donation during the past 3 months

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Crossover
Masking
Quadruple blind
Primary purpose
Basic science

Study locations

Denmark · 1 center
  • August Krogh Building — Copenhagen

Identifiers

NCT: NCT06655012 · SALM_acute

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗