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Recruiting NCT06649916

Word Learning From Parentese in Autistic Children

No phase Interventional Autism Autism Spectrum Disorder Neurodevelopmental Disorders

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Parentese Speech, Adult Registered Speech.
Who it may be relevant to
Registry conditions: Autism, Autism Spectrum Disorder, Neurodevelopmental Disorders. Basic parameters: 18 months — 59 months · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Autism Word Learning and Infant Directed-Speech

Overview

The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are factors that influence the effect of parentese on word learning (Aim 3).

Detailed description

Caregivers frequently use parentese, also known as infant-directed speech (IDS), when speaking to young children. Compared to adult registered speech, parentese is typically characterized by greater pitch variation, longer duration, and louder volume. Parentese facilitates early language development in typically developing (TD) children. However, it remains unknown whether the facilitative effect of parentese on language learning can be generalized to clinical populations such as autistic children given that core autism features (e.g., sensory and social communication differences) may interact with how they process and learn from parentese. Most autistic children do not reach age-appropriate language ability even if they receive timely early intervention. Determining if autistic children can learn language from parentese, a common way language input is provided to young children, is a critical first step toward understanding whether language input needs to be adjusted to optimize their language development.

The overall objective of this research is to determine whether parentese facilitates novel word learning in autistic children and to investigate if the effect of parentese is conditional upon input factors (recorded parentese vs live parentese presented in social interaction) and child factors (extreme responses to auditory input, social motivation). In Aim 1, the investigators will use a video-based word learning paradigm to determine the effect of recorded parentese on novel word learning in autistic children compared to language-matched TD peers. Aim 2 focuses on the effect of live parentese on novel word learning: an experimenter will teach children two novel words, presented in live parentese or live parentese, during social interaction. Aim 3 will examine whether child factors (extreme responses to auditory input, social motivation) explain variability in word learning accuracy from recorded parentese and live parentese in the autistic group. Children's extreme responses to auditory input (including hyper- and hypo-responsiveness) and social motivation will be measured using caregiver questionnaires and will be used to predict word learning accuracy from recorded parentese (Aim 1) and live parentese (Aim 2) in the autistic group.

Interventions

  • Behavioral Parentese Speech
    Novel words are introduced in parentese, a type of speech that is typically characterized by greater pitch variation, longer duration, and louder volume
  • Behavioral Adult Registered Speech
    Novel words are introduced in standard adult register.

Primary outcome measures

  • Proportion of time during which children's eye gaze is directed toward the target object [Time frame: 300 ms after the target words are introduced]

Eligibility criteria

Inclusion criteria

  • children with or without a diagnosis of ASD between 18 and 59 months

Exclusion criteria

  • hears another language more than 10% of time based on parent report
  • has uncorrected visual impairment or hearing impairment
  • has developmental disorders or medical conditions other than ASD that affect language or cognition (excepting psychiatric conditions often comorbid with ASD such as ADHD)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Non-randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Basic science

Study locations

United States · 1 center
  • University of Texas at Dallas — Richardson

Identifiers

NCT: NCT06649916 · IRB-24-616 · R21DC021803

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗