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Not yet recruiting NCT06640439

LED Therapy for Third Molar Surgery

Early Phase I Interventional Molar, Third Photobiomodulation Photobiomodulation Therapy Third Molar Surgery

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: photobiomodulation, Antibiotic.
Who it may be relevant to
Registry conditions: Molar, Third, Photobiomodulation, Photobiomodulation Therapy, Third Molar Surgery. Basic parameters: 20 years — 55 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

LED Therapy Using 830 Nm in the Mandibular Third Molar Surgery: Double-blind Randomized Clinical Trial.

Overview

LED Therapy for third molar surgery

Detailed description

LED Therapy using 830 nm in the mandibular third molar surgery

Interventions

  • Device photobiomodulation
    830 nm LED was used to irradiate the post-extraction area
  • Drug Antibiotic
    ibuprofen 0.3 g bid for 3 days, metronidazole 0.1 g tid, and cefaclor 0.375 g bid for 7 days after surgery

Primary outcome measures

  • Pain [Time frame: Day 7]
  • Swelling [Time frame: Day 3; Day 7]
  • Trismus [Time frame: Day 3; Day 7]
Secondary outcome measures (1)
  • Quality of life score [Time frame: Day 3; Day 7]

Eligibility criteria

Inclusion criteria

  • Healthy Asians;
  • 20-55 years old;
  • Having mandibular third molars that are inappropriately erupted and need to be extracted due to caries, orthodontic reasons and/or periodontal disease;

Exclusion criteria

  • Underlying diseases: diabetes, cardiovascular disease, coagulation disorder, osteoporosis, hypertension, neurological disease, psychological disorder, tumor, systemic infection or cyst at the extraction site;
  • Women who are preparing for pregnancy, pregnant or breastfeeding;
  • Medication history: use of analgesics, anti-inflammatory drugs and/or antibacterial drugs 2 weeks before tooth extraction, need for systemic medication other than acetaminophen after surgery, allergy to acetaminophen, use of anticoagulants, bisphosphonates;
  • Bad habits, such as addicted to smoking, drinking, etc.;
  • Volunteers who have recently participated in other clinical trials;

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Triple blind
Primary purpose
Treatment

Study locations

China · 1 center
  • Huashan Hospital Affiliated to Fudan University — Shanghai

Identifiers

NCT: NCT06640439 · KY2024-1088 · Self-financed

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗