Clinical Evaluation of Dimethyl Sulfoxide Wet Bonding Technique
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Universal single bond adhesive, DMSO.
- Who it may be relevant to
- Registry conditions: Dimethyl Sulfoxide. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Clinical Evaluation of Dimethyl Sulfoxide Wet Bonding Technique: A Randomized Controlled Trial
Overview
Dimethyl sulfoxide (DMSO) wet bonding has shown promising results in several in vitro studies. However, there are a lack of clinical trials which prove the advantages of this technique. The aim of the study is to clinically assess the effect of DMSO wet bonding on composite restoration in non carious cervical lesions.
Interventions
- Other Universal single bond adhesive
Will be applied and light cured for 20 seconds. - Other DMSO
DMSO application on tooth followed by active application of universal single bond adhesive and light cured for 20 seconds.
Primary outcome measures
- Fracture of material [Time frame: From treatment to 3-6 months follow up]
- Marginal adaptation [Time frame: From treatment to 3-6 months follow up]
Eligibility criteria
Inclusion criteria
- Two similar non carious cervical lesions (NCCLs) on the facial/labial surfaces of premolars.
- NCCLs of score 1-3 on the Smith and Knight tooth wear index.
- Favorable occlusion and teeth are in normal contact.
Exclusion criteria
- NCCLs on the lingual surface.
- Medically compromised individuals.
- Periodontally compromised teeth.
- Bruxism and visible wear facets in the posterior dentition.
- Fractured or visibly cracked premolars and canines.
- Known allergies to resin-based restorative materials.
- Presently undergoing orthodontic treatment.
- Abutment teeth for fixed or removable prostheses.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Factorial
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Lopez-Frias FJ, Castellanos-Cosano L, Martin-Gonzalez J, Llamas-Carreras JM, Segura-Egea JJ. Clinical measurement of tooth wear: Tooth wear indices. J Clin Exp Dent. 2012 Feb 1;4(1):e48-53. doi: 10.4317/jced.50592. eCollection 2012 Feb. PMID 24558525
- Hickel R, Mesinger S, Opdam N, Loomans B, Frankenberger R, Cadenaro M, Burgess J, Peschke A, Heintze SD, Kuhnisch J. Revised FDI criteria for evaluating direct and indirect dental restorations-recommendations for its clinical use, interpretation, and reporting. Clin Oral Investig. 2023 Jun;27(6):2573-2592. doi: 10.1007/s00784-022-04814-1. Epub 2022 Dec 12. PMID 36504246
Identifiers
NCT: NCT06635382 · 049/2023