Psychological Effects of H Pylori Associated Gastritis
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: H Pylori. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Psychological Effects of Helicopter Pylori Associated Gastritis in Patients Attending Assiut University Hospitals
Overview
The goals of this study 1. Explore association between psychological factors and Hpylori associated gastritis. 2. Assess prevalence and severity of psychology symptoms among patients with H pylori associated gastritis and their effects on their life. 3. Examine relation between demographic and clinical variables . 4. Effect of eradication of H pylori on psychological status of patients.
Detailed description
One of the most prevalant chronic bacterial illness affecting people is it H.plyori infection. it affects at least 50% of people worldwide . it is a human gastrointestinal infection which is believed to be blammed for a number of gastric illness from chronic gastritis up to gastric cancer.
numerous literature data suggest there is strong relation of anxiety disorders, stress or depression to somatic symptoms and this relation can undergo potentialization in case of appearance of pathogenic factors like helicobacter pylori infection , this relation can confirmed with many scientific reports , with the common use of antidepressants and anxiety relieving drugs in duodenal ulcer disease therapy.
The close relationship of gastrointestinal function with brain function and the mental status is known as (gut brain axis).
it has been reported that emotional factors induce changes in gastric physiology that physiological stress induces personality dependant gastric acid secretion changes and avariety of alterations in gastric motility.
. the effect of numerous stress factors which injury mucosa of stomach and modify immunity of the patient so that the patient become more sensitive to be infected with H. Pylori and infection become more aggressive and lead to manifestation of gastritis , duodenitis and gastric ulcer disease.
mental stress is considered a major pathogenic factor for peptic ulcers and it is associated with increasing prevalence of gastric ulcersin patients is with or without H.pyloriinfection.
another study revealed that depression is associated with food related symptoms as nausea and vomiting ,similarly it was showing that gastric information lead to an anxiety and depression like behaviors via neuroendocrine pathways in female not male.
so the investigetors conducted this observational study to determine the most common physiological effect is of H.pylori associated gastritis in patients attending Assiut university hospitals and How to deal with it to improve quality of life.
Primary outcome measures
- The aim of this observational study is to Explore correlation between psychological factors and H.Pylori associated gastritis . [Time frame: 2024]
Eligibility criteria
Inclusion criteria
- all patients with H.Pylori associated gastritis that diagnosed by endoscopy.
- patients diagnosed by detection of H.Pylori Ag in stool
Exclusion criteria
- patients did not take antibiotics within last 2 weeks
- patients did not take PPI within last 1 month
- patients not with acute massive GITbleeding.
- patients without eradication of H.Pylor
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06632210 · H pylori associated gastritis