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Recruiting NCT06630819

Buccal Infiltration of Different Volumes of Articaine for Extraction.

No phase Interventional Buccal Infiltration Articaine Anesthesia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: 1.8 ml of 4% Articaine, 3.6 ml of 4% Articaine.
Who it may be relevant to
Registry conditions: Buccal Infiltration, Articaine, Anesthesia. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Saudi Arabia
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Comparing the Effectiveness of Buccal Infiltration of Different Volumes of Articaine for Extraction of Mandibular Posterior Teeth- A Randomized Clinical Trial.

Overview

This study compares the effectiveness of two different volumes of buccal infiltration of Articaine for the extraction of mandibular posterior teeth. One group receives buccal infiltration of 1.8 ml of 4% Articaine and the other group receives buccal infiltration of 3.6 ml of 4% Articaine.

Detailed description

The most widely and commonly used injection method for the extraction of mandibular posterior teeth is the inferior alveolar nerve block (IANB) technique. However, various complications like pain during injection, transient facial nerve paralysis, trismus, hematoma, and paresthesia are associated with the inferior alveolar nerve block technique.

Local infiltration technique has been proven as a safer and less painful anesthetic injection technique compared to IANB. Unfortunately, the dense nature of cortical bone in the mandibular posterior region hinders sufficient diffusion of anesthetic solution during infiltration. Thus, to achieve an adequate anesthesia for a painless dental extraction of mandibular posterior teeth by infiltration technique, a strong and effective local anesthetic agent having a deeper penetrating property should be used.

Articaine is one of the most widely used local anesthetic agents. It is more potent and has shown more success rate than Lidocaine and Mepivacaine in providing anesthesia in mandibular and maxillary posterior teeth by buccal infiltration diffusibility.

This study compares the effectiveness of two different volumes of buccal infiltration of Articaine for the extraction of mandibular posterior teeth.

Interventions

  • Other 1.8 ml of 4% Articaine
    Buccal infiltration of 1.8 ml of 4% Articaine
  • Other 3.6 ml of 4% Articaine
    Buccal infiltration of 3.6 ml of 4% Articaine.

Primary outcome measures

  • Intensity of pain [Time frame: From reflection of mucoperiosteum till delivery of tooth out of socket.]
  • Time of onset of anesthesia [Time frame: upto 10 minutes]
  • Presence or absence of pain [Time frame: From reflection of mucoperiosteum till delivery of tooth out of socket.]

Eligibility criteria

Inclusion criteria

  • All healthy patients (ASA I) or patients with mild systemic disease with no functional limitations (ASA II)
  • Patients aged ≥ 18 years of age.
  • Patients requiring extraction of mandibular posterior teeth including grossly decayed tooth, grade I mobile tooth, root stumps and indicated for therapeutic reasons.
  • Patients not allergic to the drugs or anesthetic agents used in the surgery.

Exclusion criteria

  • Acute infection at the extraction site.
  • Patients indicated for surgical extraction of teeth.
  • Patients already taking medications affecting pain assessment.
  • Pregnant patients.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Saudi Arabia · 2 centers
  • Qassim University — Buraidah
  • College of Dentistry, Qassim University — Buraidah

Identifiers

NCT: NCT06630819 · 608/45/14624

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗