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Not yet recruiting NCT06630754

Body Composition in Older Adults

Observational Sarcopenia in Elderly Cachexia; Cancer; Sarcopenia Body Composition Changes Older Adults

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: No Intervention: Observational Cohort.
Who it may be relevant to
Registry conditions: Sarcopenia in Elderly, Cachexia; Cancer; Sarcopenia, Body Composition Changes, Older Adults. Basic parameters: from 70 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United Kingdom
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

An Exploration of Body Composition in Older Adults Undergoing Systemic Anticancer Treatment.

Overview

The primary aim of the study is to explore body composition in older adults (aged 70 years and over) with cancer, undergoing systemic anticancer treatment. Additional aims include to explore the extent of body composition changes and whether changes are tumour specific, the incidence for cancer-related cachexia and sarcopenia and finally, how body composition can inform nutritional management of older adults with cancer. To do this, the investigators applied for and were awarded funding from a company called Nutricia to pay for a band 4 (0.6 WTE for 7 months) to take monthly body composition measures on the patients who are eligible, accepting of assessment by the Senior Adult Oncology Programme (SAOP) and consent to these measures. Measurements will include an analysis from the Bioelectrical Impedance Analysis (BIA) machine which will quantify fat, lean muscle, and water content; waist to hip ratio; handgrip strength; calf circumferences. Socio-demographic data will also be collected. Descriptive data analysis will take place to explore possible trends and associations which may inform future research and drive even further personalised care for this growing and typically underrepresented in research, population.

Interventions

  • Other No Intervention: Observational Cohort
    No intervention; observation cohort study

Primary outcome measures

  • Explore body composition in older adults with cancer starting SACT. [Time frame: 7 months]
Secondary outcome measures (1)
  • Explore the extent of body composition changes in older adults with cancer during SACT. [Time frame: 7 months]

Eligibility criteria

Inclusion criteria

  • Adults eligible and accepting of assessment in the SAOP.
  • adults aged 70 years and over
  • a cancer diagnosis
  • just starting SACT
  • able to provide at least 2 data sets during the study period (baseline + at least 1 research clinic visit)
  • willing and able to provide written informed consent

Exclusion criteria

  • No further exclusions

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United Kingdom · 1 center
  • Royal Marsden Hospital — London

Identifiers

NCT: NCT06630754 · CCR6064

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗