Exercise-snacks for Breaking the Sedentary Lifestyle and Improving the Physical Fitness of Obese Adolescents?

Official title

Exercise-snacks: an Effective Solution for Breaking the Sedentary Lifestyle and Improving the Physical Fitness of Obese Adolescents?

Overview

The management of a person with obesity involves long-term behavioral changes with a balanced diet in both quantity and quality, along with the adoption of a more active lifestyle: increasing physical activities and reducing sedentary behaviors. The school setting has been identified as a favorable environment for interventions aimed at reducing and interrupting the time adolescents spend sitting and preventing the associated negative health consequences. Recently, very short (\< 1 minute) and intense exercises, called 'exercise-snacks,' have been reported to be effective in adults for 1) improving physical fitness over 6 weeks, and 2) improving vascular function and lowering blood glucose levels over a single day. Additionally, in adolescents with diabetes, they have been shown to reduce body fat. This raises the question of whether adding \'exercise-snack\' sessions to a multidimensional care program for hospitalized obese adolescents could further improve their physical fitness in the short and medium term. The objective of this project is to compare the effects of a traditional multidimensional care program with the addition of 'exercise-snacks' to the same care program without \'exercise-snacks\' on the physical fitness, body composition, vascular function, and physical activity and sedentary behaviors of obese children in the short and medium term. Forty-eight obese adolescents will be included. The \'exercise-snack\' group will perform six exercise sessions per day for three weeks in addition to the standard care. The control group will receive only the standard care. Assessments of physical fitness, body composition, vascular health, and questionnaires on physical activity, sedentary behavior, and cognitive restraint will be conducted at the beginning and end of the three-week program, as well as 1 and 3 months after the end of the program.

Interventions

• Other exercise-snack group
  Adolescents in the exercise-snacks group will perform 4 \"exercise-snacks\" sessions per day during 3 weeks in addition to multidimensional care program. These sessions will consist of 1-min various intense supervised exercises . They will also receive information about their attitudes to physical activity.

Primary outcome measures

• Changes in aerobic fitness: predicted VO2max [Time frame: at inclusion, at the end of the 3-weeks program and 1 and 3 month following the end of the program]

Secondary outcome measures (8)

• Changes in fat mass [Time frame: from inclusion to the end of the 3-weeks program and 1 and 3 month following the end of the program]
• Changes in body mass index in kg/m² [Time frame: at inclusion, at the end of the 3-weeks program and 1 and 3 month following the end of the program]
• change in carotid extra-media thickness [Time frame: at inclusion, at the end of the 3-weeks program and 1 and 3 month following the end of the program]
• Changes in carotid intima-thickness [Time frame: at inclusion, at the end of the 3-weeks program and 1 and 3 month following the end of the program]
• Change from baseline in carotid compliance (mm²/mmHg) [Time frame: From inclusion to the end of the 3-weeks program and 1 and 3 month following the end of the program]
• Changes in eating behaviours traits [Time frame: at inclusion, at the end of the 3-weeks program and 1 and 3 month following the end of the program]
• Changes in psychometric properties of physical activity and sedentary [Time frame: from inclusion to the end of the 3-weeks program and 1 and 3 month following the end of the program]
• change in level of habitual physical activity [Time frame: before inclusion and before the 1 and 3-month visit]

Eligibility criteria

Inclusion criteria

• Body mass index Z-score corresponding to stage 2 obesity,
• no weight loss of more than 5% of total body weight in the past 3 months,
• parental consent
• minor\'s acceptance

Exclusion criteria

• Contraindication to physical activity
• current participation in a clinical trial

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation

Randomized

Model

Parallel assignment

Masking

Open label

Primary purpose

Treatment

Study locations

France · 2 centers

• Instiutut Saint Pierre — Palavas-les-Flots
• Institut Saint Pierre — Palavas-les-Flots

Identifiers

NCT: NCT06626295 · AU_ISP1_2024

Primary sources (government registries)

• ClinicalTrials.gov (US NIH)

View this study on ClinicalTrials.gov ↗