Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: observational study.
- Who it may be relevant to
- Registry conditions: Alveolar Bone Grafting, Bone Healing, Tooth Extraction Site Healing, Wound Healing. Basic parameters: 18 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The main purpose of the study is to measure and localize immediate post extraction changes i.e. socket expansion versus no width change along the socket wall and identify whether the immediate post-extraction ridge width condition (expansion or no change) is a determinant of buccolingual ridge width and height changes 4 months following extraction and ridge preservation.
Detailed description
The null hypothesis for this study is that there is no difference in bone ridge width and height changes 4 months following extraction and alveolar ridge preservation at sites that undergo immediate post-extraction socket expansion or no immediate post-extraction ridge width change. Patients of the Graduate Periodontics Clinic at Marquette University School of Dentistry scheduled for extraction, bone graft and resorbable membrane will be recruited for this study.
After providing informed consent and prior to local anesthesia and extraction, the following parameters will be recorded: age, gender, race, medical history, medications, tooth site, reason for extraction and tooth mobility. Gingival width will be recorded prior to local anesthesia and extraction, and at 4 months. Gingival thickness will be recorded after local anesthesia and prior to extraction, and at 4 months. Buccolingual ridge width and ridge height will be recorded immediately before, immediately after extraction, and at 4 months. Immediately after extraction, the following measurements will be recorded: buccal bone thickness, number of roots, root length and width, instruments used for extraction, need for flap elevation, duration of extraction, anesthetic amount, type and approach, and operator experience.
Interventions
- Other observational study
Observational study; alveolar ridge preservation
Primary outcome measures
- Buccolingual ridge width [Time frame: (1) After local anesthesia and before extraction, (2) immediately after extraction and (3) 4 months after extraction and alveolar ridge preservation]
- Ridge height [Time frame: (1) After local anesthesia and before extraction, (2) immediately after extraction and (3) 4 months after extraction and alveolar ridge preservation]
Eligibility criteria
Inclusion criteria
- Adult patients (18-75 years)
- Good general health (controlled conditions)
- Controlled periodontal disease
- Scheduled for single tooth extraction with bone graft placement and resorbable membrane
- Tooth to be extracted must have adjacent teeth
- Socket wall integrity
Exclusion criteria
- Smoking
- Pregnancy
- Active periodontal disease
- Systemic conditions that affect healing
- Lack of socket wall integrity (bone loss ≥50 %) prior to extraction, teeth with severe infection requiring pre-extraction antibiotic treatment to control infection), and contraindications for tooth extraction.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- Marquette University School of Dentistry Graduate Periodontics Clinic — Milwaukee
Identifiers
NCT: NCT06624982 · HR-4787