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Recruiting NCT06624865

Microbiota and Carcinogenesis of Small-intestine Neuroendocrine Tumors

Observational Small-intestine Neuroendocrine Tumors

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Blood and stool sampling.
Who it may be relevant to
Registry conditions: Small-intestine Neuroendocrine Tumors. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The aim of the study is to investigate the impact of the microenvironment on tumorigenesis of small intestinal neuroendocrine tumors often located in the terminal ileum, without identified driver mutations.

Interventions

  • Other Blood and stool sampling
    Blood and stool sampling

Primary outcome measures

  • Composition of microbiota [Time frame: At day 1 and month 3]

Eligibility criteria

Inclusion criteria

  • Patient with one or more small-intestine neuroendocrine tumor with indication of surgery
  • Patient with consent for the collection, storage and reuse of data associated with his/her disease
  • Age ≥ 18 years at the time of inclusion
  • Non-objection statement obtained for participation in the study

Exclusion criteria

  • Patients with poorly differentiated neuroendocrine carcinoma or NET (neuroendocrine tumors) of non-intestinal origin or mixed tumors (MiNEN)
  • Pregnant, parturient or breast-feeding women
  • Minors
  • Persons deprived of liberty by judicial or administrative decision
  • Adults under legal protection (guardianship, curatorship)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

France · 1 center
  • Edouard Herriot University Hospital — Lyon

Identifiers

NCT: NCT06624865 · 69HCL23_1290 · 2023-A02667-38

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗