Exploring the Effect of Footbaths on Increasing the Success Rates in Vitro Fertilization
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Intelligent footbath basin.
- Who it may be relevant to
- Registry conditions: Infertility, In Vitro Fertilization. Basic parameters: 18 years — 45 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Taiwan
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Exploring the Effect of Footbaths on Increasing the Success Rates of in Vitro Fertilization and Its Associated Mechanism
Overview
To evaluate the effectiveness of warm-water footbaths in enhancing pregnancy rates during IVF and to explore the underlying mechanisms involved.
Detailed description
Additionally, this research will assess whether a complementary and alternative medicine (CAM) approach utilizing warm-water footbaths is effective in improving pregnancy rates for women undergoing IVF. Furthermore, the potential mechanisms by which footbaths may enhance IVF success rates will be elucidated.
The specific aims of this research proposal are as follows:
1. To explore the correlation between health statuses, sleep quality, stress, and infertility incidence. 2. To investigate the association between health statuses, sleep quality, stress, and multiple inflammatory indexes in infertile women, including:
2-1. Systemic immune inflammation index (SII) 2-2. Lymphocyte count (LC) 2-3. Platelet and neutrophil count product (PPN) 2-4. Platelet-lymphocyte ratio (PLR) 2-5. Neutrophil-lymphocyte ratio (NLR) 2-6. Lymphocyte-monocyte ratio (LMR) 3. The effects of Footbaths on Stress and Sleep:
To examine the effects of footbaths on reducing stress and improving sleep quality, which may enhance pregnancy success rates during IVF treatment in infertile women. 4. The impact on Inflammatory Markers:
To investigate whether footbaths can reduce levels of inflammatory markers and inflammatory cytokines during IVF treatment, potentially enhancing pregnancy success rates in infertile women.
Interventions
- Device Intelligent footbath basin
before night sleep, takes 30 mins, starting from the first day of the menstrual cycle (MC) and continuing for 28 days.
Primary outcome measures
- pregnancy rate [Time frame: 28 days]
Eligibility criteria
Inclusion criteria
- women aged 18\~45 years
- diagnosed with male factor infertility
- tubal factor infertility, or unexplained infertility, and undergoing an IVF treatment.
Exclusion criteria
- participants having adenomyosis, severe endometriosis
- a history of more than two IVF treatments
- any comorbidity or uncontrolled systemic diseases such as hypertension, diabetes, chronic heart disease or chronic renal disease that can affect the treatment process.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Taiwan · 1 center
- National Taipei University of Nursing and Health Sciences — Taipei
Identifiers
NCT: NCT06624683 · 2024-06-009BC