Two Doses of Dexmedetomidine as Adjuvent to Bupivacaine in Tap Block
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Dexmedetomidine as adjuvent to bupvacaine in tap block.
- Who it may be relevant to
- Registry conditions: Post Operative Pain. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Comparing the Analgesic Effect of Two Different Doses of Dexmedetomidine Added to Bupivacaine in Ultrasound-guided Transversus Abdominis Plane Block in Patients Undergoing Lower Abdominal Cancer Surgeries; A Randomized Clinical Trial
Overview
The aim of this study to determine the optimal dose of dexmedetomidine as an adjuvant to bupivacaine in U.S guided TAP block for preemptive analgesia In patients undergoing lower abdominal cancer surgeries.
Detailed description
The transversus abdominis plane (TAP) involves innervations of the anterolateral abdominal wall derived from T6-L1. The block can be given either by anatomical landmark technique or by using an ultrasound probe. The local anesthetic is deposited in a plane between internal oblique and transversus abdominis muscle. It provides adequate postoperative analgesia following various abdominal surgeries.Dexmedetomidine is an alpha-2 agonist that has been approved as a venous sedative and an adjuvant for pain relief .In previous studies, the addition of dexmedetomidine to bupivacaine in the TAP block has prolonged the effect of this block . So far, the optimal dose of dexmedetomidine for the TAP block has not been determined.
Interventions
- Drug Dexmedetomidine as adjuvent to bupvacaine in tap block
The analgesic effect of Two different doses of dexmedetomidine as adjuvent to bupivacaine in tap block
Primary outcome measures
- Total morphine consumption during the first 24 hours postoperatively [Time frame: First 24 hours postoperative]
Secondary outcome measures (2)
- Severity of pain using Visual analogue scale [Time frame: First 24 hours postoperative]
- Patient level of sedation using four point modified ramsy scale [Time frame: First 24 hours postoperative]
Eligibility criteria
Inclusion criteria
- age from 18 to 65 years old
- lower abdominal cancer surgery
Exclusion criteria
- patient refusal
- the local anesthetic allergy
- coagulopathy
- local infection at the procedure site
- psychic patients
- patient on chronic opioid use
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- South egypt cancer institute,Assiut University — Asyut
Identifiers
NCT: NCT06624319 · 04-2024-200895