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Not yet recruiting NCT06621680

Effect of Connective Tissue Massage on Premenstrual Syndrome

No phase Interventional Premenstrual Syndrome

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Multivitamins, Connective tissue massage.
Who it may be relevant to
Registry conditions: Premenstrual Syndrome. Basic parameters: 17 years — 25 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

This study will be conducted to investigate the effect of connective tissue massage on premenstrual syndrome.

Detailed description

Premenstrual syndrome is a collection of emotional, physiological and behavioral symptoms that develop around the end of the luteal phase and fade away with or after mensturation.

The physiological effects of connective tissue massage (CTM) are both local and general. Local effects include release of histamine from mast cells which leads to a triple response, local swelling and arteriolar dilatation mediated by local axon reflexes. The increased blood flow to the region assists resolution of subacute or chronic inflammation and reduces pain by removing nocigenic chemicals from the tissues. The mechanical distortions produced by CTM strokes help to mobilize connective tissue and improve function.

Few studies have investigated the effect of the CTM on premenstrual syndrome in adolescent females. So this study will be conducted to add new information about the effect of connective tissue massage on premenstrual syndrome, which may help adolescent females suffering from this syndrome in decreasing their symptoms, thus adding new information to the field of physical therapy.

Interventions

  • Drug Multivitamins
    All participants will receive multivitamins (vitatron) capsule once daily, for 12 weeks.
  • Other Connective tissue massage
    Connective tissue massage will be applied on (Sacral, lumbar, last thoracic vertebrae-T12, and subcostal regions), 2 sessions/week for 20 minutes each session for 12 weeks. Treatment will begin 3 days before menstruation to the 4th day of menstruation for 3 successive menstrual cycles.

Primary outcome measures

  • Pain intensity [Time frame: 3 months]
  • Premenstrual syndrome severity [Time frame: 3 months]

Eligibility criteria

Inclusion criteria

  • Virgin adolescent females diagnosed with premenstrual syndrome.
  • Their age will be ranged from 17-25 years (3 years post puberty).
  • Their body mass index (BMI) will be less than 30 kg/m2 .
  • All are of regular menstrual cycles.
  • All of them suffering from moderate and severe PMS.

Exclusion criteria

Participants will be excluded from this study if they have

  • Any pathological finding in the pelvic cavity as polycystic ovarian syndrome, endometriosis, and pelvic inflammatory diseases.
  • Irregular menstruation.
  • Any history of gynecological intervention.
  • Open wounds, weak/broken bones or fractures.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Enas Nabil Georgy — Giza

Identifiers

NCT: NCT06621680 · P.T.REC/012/005312

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗