Adjuvant VaccInation After Conization for the Treatment for CervicAL Dysplasia
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Cervical Intraepithelial Neoplasia. Basic parameters: from 18 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
The Role of Adjuvant VaccInation After Conization for the Treatment for Cervical Dysplasia
Overview
HPV vaccination has emerged as a strategy to reduce the risk of recurrence oafter excisional treatment. However, only few data are aviable. In this trial the investigators aim to assess the role of HPV vaccination in women traeted for HPV-related lesions
Detailed description
Patients treated for HPV-related disease are counseled about the potential protective role of HPV vaccination. The investigators will monitor the risk of HPV recurrence in pateints who choce to have vaccination and who did not.
Primary outcome measures
- HPV recurrence [Time frame: 2 years]
Eligibility criteria
Inclusion criteria
- Treatment of HPV-related disease
Exclusion criteria
- Previous HPV vaccination
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
Italy · 2 centers
- Fondazione IRCCS Istituto Nazionale dei Tumori — Milan
- Fondazione IRCCS Istituto Nazionale dei Tumori — Milan
Publications
- Caia C, De Maria F, Sopracordevole F, Ciavattini A, Casarin J, Ghezzi F, Vizzielli G, Chiappa V, Leone Roberti Maggiore U, Valsecchi C, Scambia G, Raspagliesi F, Corso G, Bogani G. Adjuvant VaccInation After Conization for the Treatment for CervicAL Dysplasia. Eur J Cancer Prev. 2026 May 1;35(3):243-249. doi: 10.1097/CEJ.0000000000000971. Epub 2025 Apr 18. PMID 40277212
Identifiers
NCT: NCT06611020 · 570/20